Protein Alignment Br140 and Alh

DIOPT Version :9

• Sequence 1: NP_001286155.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_001262332.1
• Gene: Alh / 40850
• FlyBaseID: FBgn0261238
• Length: 1717
• Species: Drosophila melanogaster
• Alignment Length: 1208
• Identity: 268/1208 - (22%)
• Similarity: 402/1208 - (33%)
• Gaps: 410/1208 - (33%)

  Fly   286 CCICLDGECQNTNVILFCD--MCNLAVHQDCYGVPYIPEGQWLCRRC-LQSPSKPVNCVLCPNAG 347
            ||:|.|......|.:::||  .|.:||||.|||:..:|.|.|.||:| .|..:..|.|.|||:..
  Fly    61 CCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRD 125

  Fly   348 GAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKG------LGA 406
            ||.|:||:..||||||||:||||||.|...:||| .:..||..|:..|||:|:|.|      :||
  Fly   126 GALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPI-ILSLIPQERYSKTCYICQEIGKPNRANVGA 189

  Fly   407 CIQCHRNSCYAAFHVTCAQQAGLYMT-----MDTVKDGHNDSSMHVQKFAYCHAHTPADAKLK-- 464
            |:||::::|...|||||||..||...     :|.||           ...||..|.   :|||
  Fly   190 CMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVK-----------YCGYCQHHY---SKLKKG 240

  Fly   465 ---MNVPDFEDTRHKM---------KEARKALAKKRSTAPVVLIPTIPPDRVQEIATMVTMQRKK 517
               ..:|.::..:|..         ||....:....::|.::.|.:
  Fly   241 GNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITS------------------- 286

  Fly   518 EFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRN---GIEGSPDTGELYRQLKYWQCLRQ 579
                            .:|        |.|.:..|:..:   ||.....:|.
  Fly   287 ----------------SSG--------SAGGSSNVLNASSSAGISAGSSSGS------------- 314

  Fly   580 DLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREP----- 639
                                   .:|......:.|    |.:|...:..:..|......|
  Fly   315 -----------------------GVSSSAKQRKSN----ASSKSSSSSSSSSSSSTGGAPNPSSS 352

  Fly   640 -VDTSEVPDYT---DIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDT----- 695
             |.:....:.|   .::....::|.:.        |||           .|.|...:..|
  Fly   353 SVHSGSASNMTGGGSVLPGSSNIGNIS--------NSL-----------NNNLPGGSSSTSSAGN 398

  Fly   696 VFYRAGIRMRDQAAPLFVQVRKELQRDGLLARSQRYHVDHVEAEVEQELRLLLAAPASEGIVQKL 760
            |...:|                     |:::.|                        |.|..|
  Fly   399 VPGGSG---------------------GIISAS------------------------SGGATQ-- 416

  Fly   761 LILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKARFAARHSSHANQS-QSDDEDTLGGSPSK 824
               :..||....|. .||.        |....|.....:..:||...::| .|.|:|  |...|.
  Fly   417 ---STSSQSSTAPG-TTKS--------SASSSSSSSNSYKEKHSKSLSKSTSSKDKD--GKDSST 467

  Fly   825 KRTRKRFNSSGVDMELGHDDDDEEEDSDEDSMGED-------TVSKDLLNSTQTPPCSPIKSLNN 882
            ......|.:|.......:.....|:.|.:.|..:|       |.|....:|..|.|.|...:...
  Fly   468 NSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINTQPSSSTSTATA 532

  Fly   883 SSSPVGINRRTAILLTRKAQAALKRPSEPLTTPVKEEQHNSQSSNTQSTSGSSSSVTTAATAASS 947
            .|...|.:      ::..|.:.|                ||..|.|...|..:.:::|..|.|.|
  Fly   533 GSGGTGTH------VSSSAASGL----------------NSAPSTTNEHSNHAHTLSTNGTGAGS 575

  Fly   948 GAGTLNHV-------------LSSAPPTASSFALTQNNSSGG----------------------- 976
            .||.|..|             |.|...::||   |.|:|:||
  Fly   576 AAGKLQSVSNLSNSSSGFGSDLRSVSTSSSS---TVNDSTGGFGSNSNSERENLSGAGSSASNMP 637

  Fly   977 GALASGTGIGGSSSAGT-----------AAAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPE 1030
            |.:|.||| |.||||.|           :.|.|||||:.:..|  |:|   .|.|:    |:...
  Fly   638 GTIAPGTG-GVSSSAATNLSTNKGGSSSSTANSLTSTSTSSGS--SSN---SSSKK----RKADS 692

  Fly  1031 VRHSSSMSPKKSP----NPAVT------VSQAL-PMPETLPFER-IPDSFRVYRA-----NNQRD 1078
            .:.:||:|...|.    |..::      |..|| |:.:   ||: |..|.:..|.     .:|..
  Fly   693 AKSTSSISTSGSALEDNNSLISRYDIKDVQVALTPLTD---FEKEIEKSSKRQRTELSPPTHQTS 754

  Fly  1079 VSDSDDAPSQSSSPCS------------------SCSDFSMSGSCSDFDSDEASEGDADGDPDRD 1125
            .:...:||..||:..|                  :....|:||:.....|..:|...|.|.....
  Fly   755 ATAEVNAPLASSTSASIAVTASATAASAPPATGTTTLGSSISGNAGSTSSGNSSGVSATGGAQSA 819

  Fly  1126 GGRSRSEERDSTSQEGTTDAMDMQHASLNNVQGNNGN--MAISSSS---GGSGGSSSEDDELEER 1185
            .|.....:.:|:...||..|.....:|.|.....:|:  ..|||||   ..:..|||........
  Fly   820 VGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQASTASSSSAPSLYVSV 884

  Fly  1186 PLSARQNKPMKVGTRGTPTPTTMARAVALSAGRGRGKRRSNLSESTSSTATPPPLRRAGKLRSAT 1250
            |||......:.:.|..|.:.||.....|.|  |..|.:..:..:.:::...||....||.....|
  Fly   885 PLSTANVPGINLPTSSTSSSTTSESHSASS--RSSGAQSQHQQQLSNALVGPPMGGSAGAFHGGT 947

  Fly  1251 PNA-------------SPLVNNIKARRN--------------------TTAAGS----------- 1271
            .:|             ||.:..:.:..:                    ||.:|:
  Fly   948 TSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISASGFPLPSGNLTATTTESGNLKISYEKQTTR 1012

  Fly  1272 --------APLTNNNRSKHSEDSASSERHNNHSHGQKP 1301
                    ||....:||:..|..:|....:.|.|...|
  Fly  1013 VQQLQEQEAPPARRSRSRSGESGSSHHHAHAHHHHHHP 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484
		PHD_BRPF	283..336	CDD:277047	22/52 (42%)
		ePHD_BRPF	340..456	CDD:277140	56/126 (44%)
		Bromo_brd1_like	615..712	CDD:99944	15/110 (14%)
		BR140_related	1303..1414	CDD:99900
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	20/45 (44%)
		ePHD_AF10_like	118..233	CDD:277142	56/126 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566217at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3222
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13793
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1726
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.980