Protein Alignment Br140 and Mllt10

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: XP_038951870.2
• Gene: Mllt10 / 361285
• RGDID: 1310874
• Length: 1125
• Species: Rattus norvegicus
• Alignment Length: 1182
• Identity: 257/1182 - (21%)
• Similarity: 407/1182 - (34%)
• Gaps: 378/1182 - (31%)

  Fly   242 QRLGLNAVGIDTMELL-MDR---LEKE-SHFQAAANGTPTGVEVDDDAVCCICLDGECQNTNVIL 301
            :|.|    |.:::|:: .||   ||.| ||......|.           ||:|.|......|.::
  Rat    48 ERCG----GGESLEMVSSDRPVSLEDEVSHSMKEMIGG-----------CCVCSDERGWAENPLV 97

  Fly   302 FCD--MCNLAVHQDCYGVPYIPEGQWLCRRC-LQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVC 363
            :||  .|::||||.|||:..:|.|.|.||:| .|..:..|.|.|||:..||.|:||:|.||||||
  Rat    98 YCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 162

  Fly   364 ALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKG------LGACIQCHRNSCYAAFHVT 422
            ||:||||:|||...:||| .::::|..|:..|||:|.|:|      .|||:.|:::.|..|||||
  Rat   163 ALYIPEVQFANVSTMEPI-VLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVT 226

  Fly   423 CAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLK-----------MNVPDF------ 470
            |||.|||      :.:...:.:.:||...||..|.   :|||           .::.|.
  Rat   227 CAQFAGL------LCEEEGNGADNVQYCGYCKYHF---SKLKKSKRGSNRSYDQSLSDSSSHSQD 282

  Fly   471 -----EDTRHKMKEARKALAKKRSTAPVVLIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLK 530
                 |..::|.|:..|...||:......|:|::            |:..:|.:
  Rat   283 KHHEKEKKKYKEKDKHKPKHKKQPEPSPALVPSL------------TVTTEKTY----------- 324

  Fly   531 RHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKRE 595
                         .|..|       |.|.||                             :::.|
  Rat   325 -------------TSTSN-------NSISGS-----------------------------LKRLE 340

  Fly   596 KLKVAFVRISEEVVMLQLNPLEAALNKLLDALEAR-----------DSMQIFREPVDTSEVPDYT 649
            .....|...:.:.|       .|..:...|..|||           .|.|..|:| .....|..|
  Rat   341 DTAARFTNANFQEV-------SAHTSSGKDVSEARSEGKGKKSSAHSSGQRGRKP-GGGRNPGTT 397

  Fly   650 DIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQ 714
            .....|...|:........:.:|...:::.     |:.|::.:.|   .|.......|..|....
  Rat   398 VSASSPFPQGSFSGTPGSVKSSSGSSVQSP-----QDFLSFTDSD---LRNDSYTHTQPPPSTKD 454

  Fly   715 VRKELQRDGLLARSQRYHVDHVEAEVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRTKK 779
            |.|  ...|    ||...|:...:        |:..|.:.|.
  Rat   455 VHK--GEPG----SQDAGVNSFSS--------LVGHPGTSGA----------------------- 482

  Fly   780 IKQIRLEISRMRKSLQKARFAARHSSHANQSQSDDED--TLGGSPSKKRTRKRFNSSGVDME--- 839
                                       .:|.:|.|..  .||.|.......||..:|||:.|
  Rat   483 ---------------------------TSQPKSFDSSPGELGSSSLPTAGYKRAQTSGVEEEEAV 520

  Fly   840 -----LGHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAILLTR 899
                 .|:..........:.:..::.||.  |:.:...|.|.:.|...|.:...: :::..||..
  Rat   521 KEKKRKGNKQSKHGPGRPKGNKNQENVSH--LSVSSASPTSSVASAAGSVTSCSL-QKSPTLLRN 582

  Fly   900 KAQAALKRPSEPLTTPVKEEQHNSQSSNTQSTSG----------SSSSVTTAATAASSGAGTLNH 954
            .:..:|...|.||.:.:..:..:..:..|.:.|.          :|:.|..:.....||:|:...
  Rat   583 GSMQSLSVGSSPLGSEISMQYRHDGACPTTTFSELLNAIHNGIYNSNDVAVSFPNVVSGSGSSTP 647

  Fly   955 VLSSAPPTASSFALTQNNSSGGGALASGTGIGGSSSAGTAAAASLT-STALAMNSKLSANLPVKS 1018
            |.||..|..||..|.|..:....|.:|.|....::.|.||..:||: :.|....|:|:.|
  Rat   648 VSSSHIPQQSSGHLQQVGALSPSAASSVTPAAATTQANTAPGSSLSQAPAHVYGSRLNQN----- 707

  Fly  1019 PKRPGRYRRVPEVRHSSSMSPKKSPNPAVTVSQALPMPETLPFERIPDSFRVYR--ANNQRDVSD 1081
                                    |:.||.::|:             :|.:..:  .:|.|.:..
  Rat   708 ------------------------PSMAVLIAQS-------------ESSQTDQDLGDNTRSLVG 735

  Fly  1082 SDDAPSQSSSPCSSCSDFSMSGSCSDFDSDEASEGDADGDP------DRDGGRSRSEERDSTSQE 1140
            ...:|..|.||.|..|:..:.       .|:.|....:..|      ::...|..||.:....::
  Rat   736 RGSSPRGSLSPRSPVSNLQIR-------YDQPSSSGLESLPPVAVSIEQLLERQWSEGQQFLLEQ 793

  Fly  1141 GT-TDAMDMQHASLNNVQGNNGNM--------------------------AI------------- 1165
            || :|.:.|. .||:.:|..|..:                          ||
  Rat   794 GTPSDILGML-KSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPAITTNPSPSHQIHTY 857

  Fly  1166 ------------SSSSGGSGGSSSEDDELE--ERPLSARQNKPMKVGTRGTPTPTTMARAVALSA 1216
                        ||.|...|.|...|:.|.  .:.|::............||.|...:.|   ..
  Rat   858 TAQTAPTTDSLNSSKSPHIGNSFVPDNSLPVLNQDLTSSGQSTSSSSALSTPPPAGQSPA---QQ 919

  Fly  1217 GRG-RGKRRSN-------LSESTSSTATPPPLRRAGKLRSATPNASPLVNNIKARRN-------T 1266
            |.| .|.::.|       .|...:.|:|.|.:...|.:..|.|.....:|.|....|       |
  Rat   920 GSGVSGVQQVNGVTVGPLASGMQTVTSTIPAVSAVGGIIGALPGNQLAINGIVGALNGVIQTPVT 984

  Fly  1267 TAAGSAPLTNNN 1278
            .:...||||:.:
  Rat   985 ISQNPAPLTHTS 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516
		COG5141	203..>625	CDD:227470	116/418 (28%)
		Bromo_brd1_like	615..712	CDD:99944	20/107 (19%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110	20/89 (22%)
		PWWP_BRPF	1303..1414	CDD:438964
Mllt10	XP_038951870.2	None