Protein Alignment Br140 and CG15439

DIOPT Version :9

• Sequence 1: NP_001286155.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Alignment Length: 1246
• Identity: 262/1246 - (21%)
• Similarity: 407/1246 - (32%)
• Gaps: 408/1246 - (32%)

  Fly   219 DGEVEYDVDEEDSAWLEHMNEERQRL----------GLNAVGIDTMELLMDRLEKESHFQAAANG 273
            |.|.:.|.:.|||..     :.||.|          |:|  |:|             |..|::..
  Fly    57 DSESDSDAESEDSTL-----QLRQLLAETEPSPLENGIN--GVD-------------HCAASSPA 101

  Fly   274 TP----TGVEVDD---DAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGV-------------- 317
            .|    ..:::..   ..:||:||.....:.|.|:.||.|.::||:.||||
  Fly   102 APVVPRAPLQLSSAPAKRMCCVCLGERSDDVNEIVECDSCGVSVHEGCYGVSDNVSISSTNSTCS 166

  Fly   318 --PYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEP 380
              |      |.|..|....|:| :|.||||.||.:|:||.|:|.|::|||::|.|.|.....|..
  Fly   167 TEP------WFCEACRAGVSEP-DCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLSS 224

  Fly   381 IDSIETIPPARW-RLTCYVCKEKGL----GACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGH 440
            :...| :..::| ...|.:| |..|    |.||.|....|...|||||||.||..:      :.|
  Fly   225 VTLFE-MQYSKWGAKVCSLC-ENALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLI------EAH 281

  Fly   441 NDSSMHVQKFAYCHAHTPADAKLKMNVPDFEDTR-HKMKEAR--KALAKKRSTAPVVLIPTIPPD 502
            ::.......:|:|..|:..: .:|....::...| :.|:.||  :|||.:..|      |...|:
  Fly   282 HEDDAADPFYAHCKVHSEKE-MIKKRRRNYHTLRLNMMQRAREKEALAAEHET------PAPHPN 339

  Fly   503 RVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGEL 567
            ..|     ..:|||                       |.::|.:...|
  Fly   340 PAQ-----ARIQRK-----------------------LLKIQHKYTRH----------------- 359

  Fly   568 YRQLK--YW---QCLRQDLERARLLC-ELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDA 626
             ::||  .|   |.:.:.|..:...| .|:.|.|.:.|....:.:.         ||.:|.|
  Fly   360 -KELKPTPWVPTQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQR---------EAHINAL--- 411

  Fly   627 LEARDSMQIFREPVDTSEVPDYTDIVKQ----PMDLGTMRAKLKECQYNSLEQLEADFDLMIQNC 687
                                  |||.|:    |
  Fly   412 ----------------------TDIRKKWHIAP-------------------------------- 422

  Fly   688 LAYNNKDTVFYRAGI-RMRDQAAPLFVQVRKEL-QRDGLLARSQRYHVDHVEAEVEQELRLLLAA 750
             |::.:.|.:|...| ||.|     |.|.::|| ..:.:|::.|    |.:.|:.:..|.
  Fly   423 -AFSVEFTAYYMDRIVRMDD-----FRQQQRELISHNAILSKDQ----DVLRAQYDTALE----- 472

  Fly   751 PASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRM--RKSLQKARFAARHSSHANQSQSD 813
                   ::..:.|.|..:|.:       ||.:...:.::  ..:|......|.....|....|
  Fly   473 -------ERKAVKATKDSLLTS-------IKSLHTALGQIAPNMTLPSVDLIAHPLPEAPPKTS- 522

  Fly   814 DEDTLGGSPSKKRTRKRFNSSGVDMELGH------DDDDEEEDSDEDSMGEDTVSKDLLNSTQTP 872
             ..|....|....|.... ..||...|||      ..|.....|.....|:.:.|...:.:..:.
  Fly   523 -TPTPPQRPISVPTAAAL-KMGVGFPLGHLGPPGSKMDSSRMLSTHAKQGKHSTSSASVEAAPSV 585

  Fly   873 PCSPIKSLNNSSSPVGINRRTAILLTRKAQAALKR------------PSEPLTTPVKE-EQHNSQ 924
            .|             ||.:|:      |.|..|.:            .:.|||.|.|: :|:..|
  Fly   586 SC-------------GICKRS------KDQHLLVKCDTCNLHYHLGCLNPPLTRPPKKSKQYGWQ 631

  Fly   925 SSNTQSTSGSSSSVTTAATAASSGAGTLNHVLSSAPPTASSFALTQNNSSGGGALASGTGIGGSS 989
            .|.....|..|.:||.               :||.|..:.    |:.|..|.........:....
  Fly   632 CSECCDKSEGSDAVTE---------------ISSGPRKSR----TRFNKDGHLVYVDRYSLDDIP 677

  Fly   990 SAGTAAAASLTSTALAMNSKLSANLP------VKSPKRPGRYRRVPEVRHSSSMSPKKSP--NPA 1046
            .|....... :.|..|:|..|.|..|      .||||||            ...||.|:|  .||
  Fly   678 VAAVNVPKE-SHTKRALNKSLPAPAPEYIEDLTKSPKRP------------KLQSPCKTPINVPA 729

  Fly  1047 VTVSQALPMPETLPFERIPDSFRVYRANNQRDVSDSDDAPSQSSS-PCSSCSDFSMSGSCSDFDS 1110
            ..|:   |..:..|                  |:.|...|:.:.: |..:....::|| |.|
  Fly   730 ENVT---PTTDAAP------------------VAASAATPAAAPTLPTPNTIVINLSG-CED--- 769

  Fly  1111 DEASEGDADGDPDRDGGRSRSEERDSTSQEGTTDAMDMQHASLNNVQGNNGNMAISS----SSGG 1171
               |..|:.|...|.|.|....:........|..::..:|   ...:....::..||    ::|.
  Fly   770 ---SIDDSSGKLSRKGKRKDKHKNKHNLSSDTEKSIGKEH---KRKRKKRAHLDESSTHLDNAGN 828

  Fly  1172 SGGSSSE----------DDELEERPLSARQNKPMKVGTRGTPTPT------------TMARAVAL 1214
            :.||:.:          :|..|.:......|....|.....||..            .:|..|..
  Fly   829 TSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRPTSVETVEDSVQGAEQALAPIVLP 893

  Fly  1215 SAGRGRGKRRSNLSESTSSTATPPPLRRAGKLRSATPN----ASPLVNNIKARRNTTAAGSAPLT 1275
            :|...:.:.....:.|.|...||.|.|:... |.|:|.    ..|.|:|.|.....:....:...
  Fly   894 AASPQKVREPKETAASASVNPTPSPKRKVSP-RKASPRKPRVGRPRVSNAKPNVEISCCVCSQTG 957

  Fly  1276 NNNRSKHSEDSASSERHNNHSHGQKPALEPLQLVWAKCRGYPWYPALILDPKTPKGFVYNGVPLP 1340
            .:|:....::.        |.|.....|:|......|.|||.|:.|                  .
  Fly   958 KSNQVVTCDEC--------HRHYHFACLDPPLKKSPKIRGYSWHCA------------------D 996

  Fly  1341 APPTDVLALRK 1351
            ..|||..||.|
  Fly   997 CDPTDEDALPK 1007

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484	13/54 (24%)
		PHD_BRPF	283..336	CDD:277047	19/68 (28%)
		ePHD_BRPF	340..456	CDD:277140	43/120 (36%)
		Bromo_brd1_like	615..712	CDD:99944	16/101 (16%)
		BR140_related	1303..1414	CDD:99900	14/49 (29%)
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	18/60 (30%)
		ePHD_PHF14	184..297	CDD:277144	43/120 (36%)
		PHD2_PHF14	586..635	CDD:277037	15/67 (22%)
		PHD3_PHF14	949..997	CDD:277038	11/73 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566217at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13793
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850