DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Br140 and Kdm4B

DIOPT Version :9

Sequence 1:	NP_001286155.1	Gene:	Br140 / 35648	FlyBaseID:	FBgn0033155	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_001260942.1	Gene:	Kdm4B / 318918	FlyBaseID:	FBgn0053182	Length:	717	Species:	Drosophila melanogaster

Alignment Length:	286	Identity:	67/286 - (23%)
Similarity:	110/286 - (38%)	Gaps:	47/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   746 LLLAAPASEGIVQKLLILADKSQVLK-NPTYRTKKIKQIR--LEISRMR---------KSLQKAR 798
            :|.|||....:.   ::|.||....: ||| :.|..|:..  |::..::         |::.|..
  Fly   347 VLSAAPLPPHLD---VLLCDKKMKKQCNPT-KAKSFKERNPDLDLDEIQQNPNVPDDVKAMLKES 407

  Fly   799 FAARHSSHANQSQSD--DEDTLG-GSPSKKRTRKRFNSSGVDMELGHDDDDEEED---------S 851
            .....:......::|  :||.:. .||:..:|::.....   ::.|.:|||||||         .
  Fly   408 VLTLDTGDLATDEADFPNEDAMSLQSPANLKTKQELLEY---IDDGTEDDDEEEDFKRRKQKRRY 469

  Fly   852 DEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPV--------GINRRTAILLTRKAQAALKRP 908
            |.|...:...||...||......||....:.|.||.        |..|..|....||..|..|:.
  Fly   470 DADYDDDWLASKRKTNSRNNRGRSPRTKDDRSISPASSTSSTSRGARRGKASGTPRKTPARRKKD 534

  Fly   909 SEPLTTPVKEEQHNSQSSNTQSTSGSSSSVTTAATAASSGAG-------TLNHVLSSAPPTASSF 966
            | ..|:|.......:..:.|.:....::|:.|..|..:.|.|       :|..:..|........
  Fly   535 S-ITTSPAVSSAATAVKTPTSAVVAGTTSIATTTTPPADGGGDAKKERQSLQFMQQSRKFEGKIP 598

  Fly   967 ALTQNNSSGGGALASGTGIGGSSSAG 992
            .|:|.:::.|||.|:.......||.|
  Fly   599 KLSQTSAATGGATAAAEASTSKSSQG 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484
		PHD_BRPF	283..336	CDD:277047
		ePHD_BRPF	340..456	CDD:277140
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
Kdm4B	NP_001260942.1	JmjN	11..44	CDD:280526
Kdm4B	NP_001260942.1	JmjC	173..289	CDD:202224
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900