Protein Alignment Br140 and Jade1

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: XP_006500847.1
• Gene: Jade1 / 269424
• MGIID: 1925835
• Length: 849
• Species: Mus musculus
• Alignment Length: 847
• Identity: 227/847 - (26%)
• Similarity: 348/847 - (41%)
• Gaps: 223/847 - (26%)

  Fly   178 PWAR-----VQVPVARVAEIPDYRVSDAPPRPLAYYRFIEKSLEEL------------------- 218
            ||.:     |||||:          ....|:|:|.....||||..:
Mouse    91 PWRQEWEKGVQVPVS----------PGTIPQPVARVVSEEKSLMFIRPKKYIASSGSEPPALGYV 145

  Fly   219 ------DGEVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKE-----SHFQAAAN 272
                  |....||:::.|:||||..|||.:.:|:..:...|||.:::..|:.     :|......
Mouse   146 DIRTLADSVCRYDLNDMDAAWLEVTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEE 210

  Fly   273 GTPTGVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKP 337
            |  .|:|.|:|.||.:|...:.::.|.::|||.||:.|||.|||:..:|||.||||.|......
Mouse   211 G--LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQP- 272

  Fly   338 VNCVLCPNAGGAFKQTDHG-QWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKE 401
             .|:|||..|||.|.|..| :|.||.||||||||...:...:|||..:..||.:||.|.|.:|.|
Mouse   273 -KCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 336

  Fly   402 KGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLKMN 466
            | .||.|||...:|..|||||||...||  .|.|:. ..||   .|:..:||..|:
Mouse   337 K-FGASIQCSVKNCRTAFHVTCAFDRGL--EMKTIL-AEND---EVKFKSYCPKHS--------- 385

  Fly   467 VPDFEDTRHKMKEARKALAKKRSTAP-----VVLIP--TIPPDRVQEIATMVTMQRKK------- 517
                  :..|.:|.....|.:.:.||     ..|.|  ::.|:|  |.|..|:::::|
Mouse   386 ------SHRKPEEGLGEGAAQENGAPESSPQSPLEPYGSLEPNR--EEAHRVSVRKQKLQQLEDE 442

  Fly   518 ------------------EFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDT 564
                              |.:|.:..||.|||......||:...:.:.:|  :.:|       :.
Mouse   443 FYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKINFNKPLITPKKDEEDN--LAKR-------EQ 498

  Fly   565 GELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVV-----MLQLNPLEAALNKLL 624
            ..|:|:|:.:..|||||||.|.|..:|.:|||:|.:..::.|::.     :|:...:....:...
Mouse   499 DVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFTQYTKLLEQEKVSGVPSSCS 563

  Fly   625 DALEARDSMQIFREPVDTSEVPDYTDIV-------KQPMDLGT-MRAKLKECQYNSLEQLEADFD 681
            .|||   :|..|..|......|...|:.       ||   :|| :...||:.....
Mouse   564 SALE---NMLFFNSPSVGPNAPKIEDLKWHSAFFRKQ---MGTSLVHPLKKSHKRD--------- 613

  Fly   682 LMIQNCLAYNNKDT------VFYRAGIRMRDQAAPL---FVQVR---KELQRDGLLA------RS 728
             .:||......|.:      ...|.|:.:.:....|   |.:.|   ...|::|::.      |.
Mouse   614 -AVQNSSGTEGKTSHKQPGLCGRREGLEVSESLLSLEKTFAEARLLSSAQQKNGVVTPDHGKRRD 677

  Fly   729 QRYHVDHVEAEVEQE--------LRLL---------LAAPASEGIVQ------KLLILADKSQVL 770
            .|:|.|.|:.:::.:        ||..         ..|..|.|:.|      |.::......::
Mouse   678 NRFHCDLVKGDLKDKSFKQSHKPLRSTDTSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLV 742

  Fly   771 KNPTYRTKKIKQ---IRLEISRMRKSLQKARFAARHSSHANQSQSDDEDTLGGS--PSKKRTRKR 830
            |.|......:|.   .|:.....|:...:|...|.|       |..|...||.|  |:|:|.:.|
Mouse   743 KVPITPASPVKSWGGFRIPKKGERQQQGEAHDGACH-------QHSDCSHLGVSRAPAKERAKSR 800

  Fly   831 FNSSGVDMEL-GHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTA 894
            ..:   |.|. |:..|.|..||:.::                   |..|.::.||:   |:|||.
Mouse   801 LRA---DSENDGYAPDGEMSDSESEA-------------------SEKKCIHASST---ISRRTD 840

  Fly   895 IL 896
            |:
Mouse   841 II 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516
		COG5141	203..>625	CDD:227470	150/489 (31%)
		Bromo_brd1_like	615..712	CDD:99944	20/113 (18%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110
		PWWP_BRPF	1303..1414	CDD:438964
Jade1	XP_006500847.1	COG5141	115..>543	CDD:227470	147/464 (32%)
		ePHD_JADE	274..384	CDD:277141	55/116 (47%)