DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Br140 and Kdm4d

DIOPT Version :9

Sequence 1:	NP_001286155.1	Gene:	Br140 / 35648	FlyBaseID:	FBgn0033155	Length:	1430	Species:	Drosophila melanogaster
Sequence 2:	NP_775609.2	Gene:	Kdm4d / 244694	MGIID:	3606484	Length:	510	Species:	Mus musculus

Alignment Length:	207	Identity:	46/207 - (22%)
Similarity:	78/207 - (37%)	Gaps:	60/207 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   995 AAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPEVRHSSSMSPKKSPNPAVTVSQALPMPETL 1059
            |....|.|.::.:.:|:.....|:|::....:|: .:|..|     :|..|..|||
Mouse   340 AVVDHTETMVSTSQELTTRRVTKAPRKTWGLKRL-RLRQVS-----RSLLPIATVS--------- 389

  Fly  1060 PFERIPDSFRVYRANNQ------RDVSDSDDAPSQSSSPCSSCSDFSMS-GSCS------DFDSD 1111
               .:|.:.:|...:.|      .||..||.|.: |..|.|..|...|| ..||      :..:.
Mouse   390 ---NVPCNMQVCHTSRQPSDVKGDDVQKSDSARA-SPHPLSLPSSGHMSTRRCSLGRRPCELGAQ 450

  Fly  1112 EASEGDADGDPDRDGGRSRSEERDSTSQEGTTDAMDMQHASLNNVQGNNGNMAISSS-------- 1168
            |:|    :|.|.:   |.....||.||     .:.::|      .|..:|::.:.|.
Mouse   451 ESS----NGAPVK---RQLPAGRDDTS-----PSPELQ------PQAVSGDLIVDSGLVNPGPQH 497

  Fly  1169 --SGGSGGSSSE 1178
              :...||.:|:
Mouse   498 LMTASEGGLTSD 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_001286155.1	EPL1	<192..264	CDD:287484
		PHD_BRPF	283..336	CDD:277047
		ePHD_BRPF	340..456	CDD:277140
		Bromo_brd1_like	615..712	CDD:99944
		BR140_related	1303..1414	CDD:99900
Kdm4d	NP_775609.2	JmjN	15..55	CDD:128818
		JmjC	176..292	CDD:334913
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..510		31/132 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5141
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900