Protein Alignment Gadd45 and GADD45A

DIOPT Version :10

• Sequence 1: NP_610264.1
• Gene: Gadd45 / 35646
• FlyBaseID: FBgn0033153
• Length: 163
• Species: Drosophila melanogaster
• Sequence 2: NP_001915.1
• Gene: GADD45A / 1647
• HGNCID: 4095
• Length: 165
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 41/152 - (26%)
• Similarity: 72/152 - (47%)
• Gaps: 28/152 - (18%)

  Fly    31 IGRTIKSALLRAQSEARVIVGLSAAINVLSKSPEGSLFCLMAQPKDGDS--ATHMHEVLLEAFCY 93
            :|..::..|.:|.|:..:.||:..|..:|:..|:..:.||:|..:|.|.  |..:|..|::|||.
Human    19 VGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCC 83

  Fly    94 ENDIYVIKVDDATKLSRIL---------GQDSVES-----CCLV----QKVWADAPEEQLTKAEN 140
            ||||.:::|.:..:|:.:|         ..:..|.     |.||    ...|.|       .|.:
Human    84 ENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKD-------PALS 141

  Fly   141 QLVDYC-EAHWDAPQQPIVQLP 161
            ||:.:| |:.:.....|::.||
Human   142 QLICFCRESRYMDQWVPVINLP 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gadd45	NP_610264.1	None
GADD45A	NP_001915.1	Ribosomal_L7Ae	21..123	CDD:426153	27/101 (27%)