DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gadd45 and Gadd45a

DIOPT Version :9

Sequence 1:NP_610264.1 Gene:Gadd45 / 35646 FlyBaseID:FBgn0033153 Length:163 Species:Drosophila melanogaster
Sequence 2:NP_031862.1 Gene:Gadd45a / 13197 MGIID:107799 Length:165 Species:Mus musculus


Alignment Length:182 Identity:46/182 - (25%)
Similarity:81/182 - (44%) Gaps:40/182 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MVVEENCSMHHLERELDLELEIDMAMECAPIGRTIKSALLRAQSEARVIVGLSAAINVLSKSPEG 65
            |.:||..:.......:|            .:|..::..|.:|:|:..:.||:..|..:|:..|:.
Mouse     1 MTLEEFSAAEQKTERMD------------TVGDALEEVLSKARSQRTITVGVYEAAKLLNVDPDN 53

  Fly    66 SLFCLMAQPKDGDS--ATHMHEVLLEAFCYENDIYVIKVDDATKLSRILGQDS----VES----- 119
            .:.||:|..:|.|.  |..:|..|:.|||.||||.:::|.:..:|:.:|..::    .||     
Mouse    54 VVLCLLAADEDDDRDVALQIHFTLIRAFCCENDINILRVSNPGRLAELLLLENDAGPAESGGAAQ 118

  Fly   120 -----CCLV----QKVWADAPEEQLTKAENQLVDYC-EAHWDAPQQPIVQLP 161
                 |.||    ...|.|       .|.:||:.:| |:.:.....|::.||
Mouse   119 TPDLHCVLVTNPHSSQWKD-------PALSQLICFCRESRYMDQWVPVINLP 163

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gadd45NP_610264.1 None
Gadd45aNP_031862.1 Ribosomal_L7Ae 21..105 CDD:366537 26/83 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167847446
Domainoid 1 1.000 56 1.000 Domainoid score I10960
eggNOG 1 0.900 - - E1_2C91W
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 62 1.000 Inparanoid score I5378
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001094
OrthoInspector 1 1.000 - - otm44036
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR10411
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X821
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1211.850

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