Protein Alignment Gadd45 and GADD45G

DIOPT Version :9

• Sequence 1: NP_610264.1
• Gene: Gadd45 / 35646
• FlyBaseID: FBgn0033153
• Length: 163
• Species: Drosophila melanogaster
• Sequence 2: NP_006696.1
• Gene: GADD45G / 10912
• HGNCID: 4097
• Length: 159
• Species: Homo sapiens
• Alignment Length: 147
• Identity: 41/147 - (27%)
• Similarity: 68/147 - (46%)
• Gaps: 28/147 - (19%)

  Fly    32 GRTIKSALLRAQSEARVIVGLSAAINVLSKSPEGSLFCLMA--QPKDGDSATHMHEVLLEAFCYE 94
            |:.:...||.||.:..:..|:..:..||:..|:...||::|  :..:||.|..:|..|::|||.|
Human    23 GKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEGDIALQIHFTLIQAFCCE 87

  Fly    95 NDIYVIKVDDATKLSRILGQDSVES------CCLV----QKVWADAPEEQLTKAENQLVDYCEA- 148
            |||.:::|.|..:|:.|:|......      |.|:    :..|.|...|:|:.       :||.
Human    88 NDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCILISNPNEDAWKDPALEKLSL-------FCEES 145

  Fly   149 ----HWDAPQQPIVQLP 161
                .|    .|.:.||
Human   146 RSVNDW----VPSITLP 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gadd45	NP_610264.1	None
GADD45G	NP_006696.1	Ribosomal_L7Ae	24..>106	CDD:307418	27/81 (33%)
		Homodimerization	43..86		13/42 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157039
Domainoid	1	1.000	57	1.000	Domainoid score	I10877
eggNOG	1	0.900	-	-		E1_2C91W
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	61	1.000	Inparanoid score	I5391
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1517160at2759
OrthoFinder	1	1.000	-	-		FOG0001094
OrthoInspector	1	1.000	-	-		otm41986
orthoMCL	1	0.900	-	-		OOG6_113955
Panther	1	1.100	-	-	O	PTHR10411
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4846
SonicParanoid	1	1.000	-	-		X821
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790