Protein Alignment Spn43Ad and SERPINB12

DIOPT Version :9

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 88/438 - (20%)
• Similarity: 164/438 - (37%)
• Gaps: 90/438 - (20%)

  Fly    35 SSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKLAVQ 99
            ::.:|...|..::|......|:..|||.:.|||.::...:.|:...|:.:.|.....|..:....
Human    19 ANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEP 83

  Fly   100 D------FETLLTDL--------------------KQSAAIGC----------------RLRLLS 122
            |      .:.:|.|.                    .:|..:.|                .|.:.:
Human    84 DPCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIAN 148

  Fly   123 DLYAQQRFTF----------NFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLG 177
            .||.:|.|..          .:....|::..:          ::...:.|:||:....:|...:.
Human   149 RLYGEQEFPICQEYLDGVIQFYHTTIESVDFQ----------KNPEKSRQEINFWVECQSQGKIK 203

  Fly   178 ELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRY 242
            ||.|...:.:    .|..:.|:.|.|:|.|...||...|....|....|..:.|..|..:..||.
Human   204 ELFSKDAINA----ETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRI 264

  Fly   243 AEVPALDAQLIEVPFATADLRMLIVFPNRP----DGLAQLERKLAQSDLHQLRS--QLEERKVAL 301
            ..:..:.||::|:.:....|.|.::.|:..    .||.:||||:....:....|  .:.|..|.|
Human   265 GFIEEVKAQILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVL 329

  Fly   302 TLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPP---LGAVVQSGLLELQEDG 363
            :.|:..:....||..:|:::|:..:|      .|..:.:...|..|   |..::....:|:.|:|
Human   330 SFPRFTLEDSYDLNSILQDMGITDIF------DETRADLTGISPSPNLYLSKIIHKTFVEVDENG 388

  Fly   364 GNADDSFSFGDL-----FRRALPLVINHPFFYAIGNGK--TLLLSGHI 404
            ..|  :.:.|.:     .|..:....||||.:.|.:.|  |:|..|.:
Human   389 TQA--AAATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	88/436 (20%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	88/438 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920