DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and SERPIN1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001320925.1	Gene:	SERPIN1 / 841182	AraportID:	AT1G47710	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	421	Identity:	96/421 - (22%)
Similarity:	166/421 - (39%)	Gaps:	85/421 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVS-SNRFGLRLTTKLGLT-QPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASH-P 94
            |:| .|:..:.|...:..| ..::||:.||..|...||::.|.|:.....|:...|:.:.... .
plant    33 SISLQNQVSMNLAKHVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTDQLN 97

  Fly    95 KLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRLSWESASN 159
            ..:.:....:|.|  .||..|.:|.:.:..:..:  :.:|:..|:.|...        |:::|||
plant    98 SFSSEIVSAVLAD--GSANGGPKLSVANGAWIDK--SLSFKPSFKQLLED--------SYKAASN 150

  Fly   160 AAQDINYAFLSRSNFSLGE-----------LVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDP 213
            .|.     |.|::...:.|           |::....|..|:..|..:..:.:.|:..|...||.
plant   151 QAD-----FQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDE 210

  Fly   214 TETQSINF-----------FAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLR---M 264
            :.||...|           |....:.:.|.|..|   ::...:|.|..|         |.|   |
plant   211 SLTQEGEFHLLDGNKVTAPFMTSKKKQYVSAYDG---FKVLGLPYLQGQ---------DKRQFSM 263

  Fly   265 LIVFPNRPDGLAQLERKLAQS----DLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAK 325
            ....|:..:||:.|..|:..:    |.|..|.|::.|:  ..:||.:.....|..:||:.|||..
plant   264 YFYLPDANNGLSDLLDKIVSTPGFLDNHIPRRQVKVRE--FKIPKFKFSFGFDASNVLKGLGLTS 326

  Fly   326 LFTSEVHLSEVFSSILSSSAPPLGA------VVQSGLLELQEDGGNADDSFSFGDLFRRAL---- 380
            .|:.|..|:|:..|      |.:|.      :.....:|:.|:|..| .:.|.|.:..|.|
plant   327 PFSGEEGLTEMVES------PEMGKNLCVSNIFHKACIEVNEEGTEA-AAASAGVIKLRGLLMEE 384

  Fly   381 ---PLVINHPFFYAIGNGKT--LLLSGHIVD 406
               ..|.:|||...:....|  :|..|.:||
plant   385 DEIDFVADHPFLLVVTENITGVVLFIGQVVD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	93/415 (22%)
SERPIN1	NP_001320925.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010