DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpina7

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_112390.1	Gene:	Serpina7 / 81806	RGDID:	619833	Length:	426	Species:	Rattus norvegicus

Alignment Length:	415	Identity:	99/415 - (23%)
Similarity:	171/415 - (41%)	Gaps:	63/415 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LPVDGELLARSPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQ 84
            ||.....|.:.| |:::: |..||..||.:..||.|:..||:.|.|||::|...|.|...:|:.:
  Rat    43 LPQQNATLYKMP-SINAD-FAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILE 105

  Fly    85 ALELTHASHP-KLAVQDFETLLTDLK-----------QSAAIGCRLRLLS-------DLYAQQRF 130
            .|.......| |...|.|:.|:..|.           .:..||.:|:.|:       .||..:.|
  Rat   106 VLGFNLTDTPVKELQQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVF 170

  Fly   131 TFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPF 195
            :.:|.|                    .|.|..:|| :::.:.  :.|::|...|...|   |...
  Rat   171 STDFSN--------------------VSAAQHEIN-SYVEKQ--TKGKIVGLIQDLKL---NIIM 209

  Fly   196 LHVSGVTFRAPWAWAFDPTET-QSINFFAGGNRPRLVDAMFG-QHRYRYAEVPALDAQLIEVPFA 258
            :.|:.:.|:|.||..|..::| :|.||....:....|..|.. :..|.|.:| .|:..::::.:
  Rat   210 ILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPMMHQLEQYYHYVDV-ELNCTVLQMDY- 272

  Fly   259 TADLRMLIVFPNRPDGLAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGL 323
            :|:...|.|.| :...:..:|..::...|.:....|::..|.|.:||..:....||...|:::|:
  Rat   273 SANALALFVLP-KEGHMEWVEAAMSSKTLKKWNHLLQKGWVELFVPKFSISATYDLGSTLQKMGM 336

  Fly   324 AKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFR-RALPL----V 383
            ...|..    |..|..|...:...|.......:|.:.|:|.....|...|.|.: ...||    .
  Rat   337 RDAFAE----SADFPGITKDNGLKLSYAFHKAVLHIGEEGTKEGASPEAGSLDQPEVAPLHAVIR 397

  Fly   384 INHPFFYAIGNGKT--LLLSGHIVD 406
            ::..|...|...:|  :|..|.:||
  Rat   398 LDRTFLLMILEKRTRSVLFLGKVVD 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	92/396 (23%)
Serpina7	NP_112390.1	serpinA7_TBG	48..425	CDD:381023	97/410 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100