Protein Alignment Spn43Ad and SERPINA7

DIOPT Version :10

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 81/368 - (22%)
• Similarity: 150/368 - (40%)
• Gaps: 69/368 - (18%)

  Fly    32 ASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKL 96
            :|:::: |...|..:..:..||.|:..||:.|.|||.:|...:.....:::.:.|.......|.:
Human    43 SSINAD-FAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMV 106

  Fly    97 AVQ-DFETLLTDLK-----------QSAAIGCRL----RLLSD---LYAQQRFTFNFRNEFETLA 142
            .:| .|:.|:..|.           .:..||..|    :.|:|   ||..:.|:.:|.|
Human   107 EIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSN------ 165

  Fly   143 ARMGVGCHRLSWESASNAAQDINYAFLSRSNFSL---GELVSAPQLESLAEHNTPFLHVSGVTFR 204
                          .|.|.|:||      |:..:   |::|..  ::.| :.||..:.|:.:.|:
Human   166 --------------ISAAKQEIN------SHVEMQTKGKVVGL--IQDL-KPNTIMVLVNYIHFK 207

  Fly   205 APWAWAFDPTETQ-SINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVF 268
            |.||..|||::|: |.:|.........|..|....:|.:.....|:..::::.::...| .|.|.
Human   208 AQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNAL-ALFVL 271

  Fly   269 PNRPDGLAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHL 333
            | :...:..:|..::...|.:....|::..|.|.:||..:....||...|.::|:...::....
Human   272 P-KEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD- 334

  Fly   334 SEVFSSI-----LSSSAPPLGAVV-----QSGLLELQEDGGNA 366
               ||.:     |..|..|.|.|:     ...:|.:.|.|..|
Human   335 ---FSGLTEDNGLKLSNRPAGFVLPTQAAHKAVLHIGEKGTEA 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	serpin42Dd-like_insects	34..407	CDD:381070	80/366 (22%)
SERPINA7	XP_006724746.1	serpinA7_TBG	37..425	CDD:381023	81/368 (22%)