DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpina5

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001231668.1	Gene:	Serpina5 / 65051	RGDID:	619817	Length:	442	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	91/409 - (22%)
Similarity:	158/409 - (38%)	Gaps:	72/409 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SPASVSSNR---FGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELT-H 90
            |..:|.::|   |..||...|....|..||..||:.:..:|.:|...|..:..:|:.:.|.|: .
  Rat    71 SVGAVGTSRSRDFAFRLYRALASEAPGQNVFFSPMSVSMSLGMLSLGSGLKTKAQILEGLGLSLQ 135

  Fly    91 ASHPKLAVQDFETLLTDLKQSA---------------AIGCR---LRLLSDLYAQQRFTFNFRNE 137
            .....:..:.|:.||....|.:               |:..|   |..:..||....|:.||.|
  Rat   136 QGQEDMLHKGFQQLLQQFSQPSDGLQLSLGSALFTDPAVHIRDHFLSAMKTLYMSDMFSTNFGN- 199

  Fly   138 FETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVT 202
                               ..:|.:.||.....::|..:.:|:.  .|:|        .||..|.
  Rat   200 -------------------PESAKKQINDYVAKKTNGKIVDLIK--DLDS--------THVMVVV 235

  Fly   203 ----FRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLR 263
                |:|.|..||..|.|..:::.....:...|..|..:..|.|.....:...::.:|: ..:..
  Rat   236 NYIFFKAKWQTAFSSTNTHKMDYHVTPKKTIQVPMMNREDIYSYILDQNISCTVVGIPY-QGNTF 299

  Fly   264 MLIVFPNRPDG-LAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLF 327
            .|.:.|:  :| :.::|..|.:..|........:|::.|.|||..:.....|:.:|.:||:..:|
  Rat   300 ALFILPS--EGKMKRVEDGLDERTLRNWLKMFTKRQLDLYLPKFSIEGTYKLEKILPKLGIQDIF 362

  Fly   328 TSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLF--RRALP----LVINH 386
            |:...|    |.:...:...|..:|...::|:.|.|..|  :.|.|.||  |.|.|    :....
  Rat   363 TTHADL----SGLTDHTNIKLSEMVHKSMVEVDESGTTA--AASTGILFTLRSARPSSLKVEFTR 421

  Fly   387 PFFYAIGNGKTLLLSGHIV 405
            ||...|.:|..|...|.::
  Rat   422 PFLVVIMDGTNLYFIGKVI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	89/401 (22%)
Serpina5	NP_001231668.1	alpha-1-antitrypsin_like	81..439	CDD:239011	88/396 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100