Protein Alignment Spn43Ad and SERPINB4

DIOPT Version :9

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 90/379 - (23%)
• Similarity: 163/379 - (43%)
• Gaps: 62/379 - (16%)

  Fly    55 NVVVSPLLIQAALSLLYAESSSEYGSQLRQAL---ELTHASHPKLAV----------QDFETLLT 106
            |:..||:.|.:||.::...:......|:.:.|   ::|..:..|.|.          ..|:.|||
Human    26 NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQFQKLLT 90

  Fly   107 DLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRLSWESA--SNAAQD----IN 165
            :..:|.. ...|::.:.|:.::  |:.|..|:.....:.    ::.|.||.  :||.::    ||
Human    91 EFNKSTD-AYELKIANKLFGEK--TYQFLQEYLDAIKKF----YQTSVESTDFANAPEESRKKIN 148

  Fly   166 YAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRL 230
            ....|::|..:..|..    :....::|..:.|:.:.|:..|...|....|:...|:...|..:.
Human   149 SWVESQTNEKIKNLFP----DGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKS 209

  Fly   231 VDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKLAQSDLHQLRS--Q 293
            |..|...:.:.:|.:..:.|:::|:|:...||.|:::.||..|||.:||.||....|.:..|  .
Human   210 VQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQN 274

  Fly   294 LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEV-FSSILSSSAPPLGAVVQSGLL 357
            :.|..|.|.||:.::....|||..|..:|:..:|..:..||.: :|..||.|     .|:....:
Human   275 MRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVS-----KVLHKAFV 334

  Fly   358 ELQEDGGNADDSFSFGDLFRRALPLVI--------------NHPFFYAIGNGKT 397
            |:.|:|..|          ..|..:|:              ||||.:.|...||
Human   335 EVTEEGVEA----------AAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKT 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	90/379 (24%)
SERPINB4	NP_002965.1	SERPIN	4..390	CDD:320777	90/379 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920