Protein Alignment Spn43Ad and SERPINB3

DIOPT Version :9

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 90/374 - (24%)
• Similarity: 163/374 - (43%)
• Gaps: 52/374 - (13%)

  Fly    55 NVVVSPLLIQAALSLLYAESSSEYGSQLRQAL---ELTHASHPKLAV----------QDFETLLT 106
            |:..||:.|.:||.::...:......|:::.|   ::|..:..|.|.          ..|:.|||
Human    26 NIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLT 90

  Fly   107 DLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRLSWESA--SNAAQD----IN 165
            :..:|.. ...|::.:.|:.::  |:.|..|:.....:.    ::.|.||.  :||.::    ||
Human    91 EFNKSTD-AYELKIANKLFGEK--TYLFLQEYLDAIKKF----YQTSVESVDFANAPEESRKKIN 148

  Fly   166 YAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRL 230
            ....|::|..:..|:....:.|    ||..:.|:.:.|:..|...|:..:|:...|:...|..:.
Human   149 SWVESQTNEKIKNLIPEGNIGS----NTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKS 209

  Fly   231 VDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKLAQSDLHQLRS--Q 293
            :..|.....:.:|.:..:.|:::|:|:...||.|:::.||..|||.:||.||....|.:..|  .
Human   210 IQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQN 274

  Fly   294 LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLE 358
            :.|.:|.|.||:.:|....|||..|..:|:..:|..:..|    |.:..|....|..|:....:|
Human   275 MRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADL----SGMTGSRGLVLSGVLHKAFVE 335

  Fly   359 LQEDGGNA----------DDSFSFGDLFRRALPLVINHPFFYAIGNGKT 397
            :.|:|..|          ....|..:.|.      .||||.:.|...||
Human   336 VTEEGAEAAAATAVVGFGSSPTSTNEEFH------CNHPFLFFIRQNKT 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	90/374 (24%)
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	90/374 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920