DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and si:ch211-186e20.7

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_021329695.1	Gene:	si:ch211-186e20.7 / 566630	ZFINID:	ZDB-GENE-110407-6	Length:	410	Species:	Danio rerio

Alignment Length:	443	Identity:	98/443 - (22%)
Similarity:	164/443 - (37%)	Gaps:	94/443 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LVGLAIAL-----TL---PVDGELLARSPASVS-SNRFGLRLTTKLGLTQPD---ANVVVSPLLI 63
            :.|.||.:     ||   |:..:|    |:.:: :|.|...|..:: :..||   .|:..||..:
Zfish    10 IFGFAIVVCGNQETLQQPPISAKL----PSLINMNNDFAFHLYKRV-IESPDYQSKNIFFSPFSV 69

  Fly    64 QAALSLLYAESSSEYGSQLRQALEL------THASHPKLAVQDFETLLTDLKQSAA----IGCRL 118
            ..|||.|...:..:...||...:..      |...|     |.|.:||.|:.....    :|..|
Zfish    70 SIALSELSLGAGGDTKQQLLSGIGYNSTTFSTEEMH-----QLFHSLLEDIGNRTGVDIDVGTAL 129

  Fly   119 ----------RLLSDL---YAQQRFTFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLS 170
                      :.|.|:   |....||.:||.: ||:                   .|..|||
Zfish   130 YASDRFKPHSKFLEDMKEFYHSDGFTVDFRVK-ETV-------------------DQINNYA--- 171

  Fly   171 RSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMF 235
             ...:.|:...|  ::.|.|....|| ::.:.|:..|...|.|.:|:...|.........|..|
Zfish   172 -KKKTQGKFNQA--VDDLEEDTLMFL-LTYIYFKGKWDKPFKPEKTRESTFHIDDKTTVPVQMM- 231

  Fly   236 GQHRYRYAEVPALDAQLIEVPFATADLR----MLIVFPN---RPDGLAQLERKLAQSDLHQLRSQ 293
              |:|...:| ..||:| .......|.:    |.:..|:   ....:..||..:::....:.|..
Zfish   232 --HQYERLKV-FYDAEL-STKVLCLDYKDSFSMFLAVPDDKMEHKNIKDLEMTVSRQHFEKWRRS 292

  Fly   294 LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLE 358
            ..::.|.:.:|||.:.....||.:|:.:|:|.:|:.:.:.:.|     |.....:..|:....|:
Zfish   293 AFKKTVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKANFTGV-----SEEKIFVSKVLHKATLD 352

  Fly   359 LQEDGGNADDSFSFGDLFRRALPLVI---NHPF--FYAIGNGKTLLLSGHIVD 406
            :.|.|..|..........|...||.|   |.||  |........:|..|.:|:
Zfish   353 IDEQGTTAAAVTGVSMRVRLHNPLSILKFNRPFMVFITDQTNDNILFFGKVVN 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	89/407 (22%)
si:ch211-186e20.7	XP_021329695.1	alpha-1-antitrypsin_like	39..403	CDD:239011	89/406 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110