DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinf2b

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001073479.1	Gene:	serpinf2b / 563663	ZFINID:	ZDB-GENE-061215-114	Length:	479	Species:	Danio rerio

Alignment Length:	383	Identity:	98/383 - (25%)
Similarity:	163/383 - (42%)	Gaps:	52/383 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DGELLARSPASVSSN---RFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQ 84
            ||::..:.......|   :.||.....|..:....||:.|||.:..|||.|...::::....|
Zfish    92 DGDMTGKQIKRTIGNGIMKLGLLFLENLKPSPDQPNVIFSPLSLSVALSQLALGATNDTEELL-- 154

  Fly    85 ALELTHASHPKLAVQDFETLLTDL-----KQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAAR 144
             |...||.    |:..:.|.|:.|     |:|..|..|:.|.:...|:..|..:.:..:::..|.
Zfish   155 -LHHLHAD----ALPCYHTALSSLLRNFRKRSMPIASRIYLKTGFKAKSDFMEDSQKLYDSEPAT 214

  Fly   145 MGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAW 209
            :             ....|:|......:|..:.|.:|     ||.......| ::.:.::..|..
Zfish   215 L-------------TDVNDVNEWVKKVTNGHISEFLS-----SLPPSAVMML-INAMHYKGEWLT 260

  Fly   210 AFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVP--ALDAQLIEVPFATADLRMLIVFPNRP 272
            .|||..|.:.||:...|:...||.|.|. :|..:...  .||||:...|| ..|..:|:|.|...
Zfish   261 RFDPHFTSTENFYIDENQIVNVDMMLGP-KYPLSVFTHHELDAQVARFPF-KGDRSLLVVMPTSG 323

  Fly   273 D-GLAQLERKLAQSDLHQLRSQL-EERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSE 335
            . .::.:..||..|||:   |:| .||.:.:.|||.::..:.||:..:..:||.||| |...|..
Zfish   324 HVNVSAIAAKLNISDLY---SRLPRERNMQVKLPKFKLDFNQDLQEAMTSMGLGKLF-SHPKLDR 384

  Fly   336 VFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALP-LVINHPFFYAI 392
            :....|..|     :|.....:|:.|:|..|..:.|.  :..|:.| ..:|.|||:|:
Zfish   385 ITEGPLFVS-----SVQHMSSVEINEEGAEAVAATSV--VISRSNPSFTVNQPFFFAL 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	96/371 (26%)
serpinf2b	NP_001073479.1	SERPIN	106..449	CDD:294093	96/369 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100