DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinf2a

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_688797.1	Gene:	serpinf2a / 560308	ZFINID:	ZDB-GENE-060822-1	Length:	457	Species:	Danio rerio

Alignment Length:	399	Identity:	101/399 - (25%)
Similarity:	165/399 - (41%)	Gaps:	73/399 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLSALLVGLAIALTLPVDGELLARSPASVSSNRFGLRLTTKL--GLTQPDANVVVSPLLIQAALS 68
            |.|...||.|:|                    :.||.|..||  |..||  |:::|||.:..||:
Zfish    37 LESQRAVGAAVA--------------------KLGLTLLEKLQPGSEQP--NIIISPLSVSLALA 79

  Fly    69 --LLYAESSSEYGSQLRQALELTHASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQRFT 131
              .|.|.:::|     .:.||:.||..    :..|...|:.|::...... :::.|.||....:|
Zfish    80 ELALGARNNTE-----EKLLEVLHAKE----LPHFHETLSCLQEHLTAKA-VKMASRLYLVPGYT 134

  Fly   132 FNFRNEFETLAARMGVGCHRLSWESAS-NAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPF 195
            .|  .:|...|..:      ...|||. .:.:|:|......:|..:...:|:      ...|...
Zfish   135 VN--PDFVDRALNL------YKSESAQLTSIEDVNRWVEETTNGQITNFMSS------LPPNVVL 185

  Fly   196 LHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALD-AQLIEVPFAT 259
            :.::.:.|:..|...|:...|:...|.........||.|.|........|...| .|:..:|| .
Zfish   186 MLINAIHFKGEWQSRFNSKYTKENIFHIDRKTSVKVDMMMGSQYPLSMFVDRTDGTQVARLPF-R 249

  Fly   260 ADLRMLIVFPN-RPDGLAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGL 323
            .::.:|::.|. :.:.|:.:..||..||::....:  ||.:.:||||.::....||:..|..:||
Zfish   250 GNMSLLVIMPRLQHENLSNVAAKLNISDMYARFPR--ERSMHVTLPKFKLEYKQDLRQALTSMGL 312

  Fly   324 AKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGL-----LELQEDGGNADDSFSFGDLFRRALPLV 383
            ..|||         ...||..||  |.:|.||:     :||.|:|..|..:.|| .|.|......
Zfish   313 GFLFT---------GPDLSRIAP--GPLVVSGVQHASNMELSEEGAEASAATSF-TLVRTISFFS 365

  Fly   384 INHPFFYAI 392
            :|.||.:|:
Zfish   366 VNMPFIFAL 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	95/370 (26%)
serpinf2a	XP_688797.1	SERPIN	54..388	CDD:294093	93/362 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100