DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinb9h

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001357856.1	Gene:	Serpinb9h / 544923	MGIID:	3709608	Length:	377	Species:	Mus musculus

Alignment Length:	391	Identity:	88/391 - (22%)
Similarity:	165/391 - (42%)	Gaps:	44/391 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKLA 97
            |.::..|.:.|...|....|..||..||:.|.:||:::...:..:...|:.|||.|    :|...
Mouse     5 SQANGTFAIHLLKVLCQDNPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALHL----NPDED 65

  Fly    98 V-QDFETLLTDL-KQSAAIGCRLRLLSDLYAQQRF----TFN------FRNEFETLAARMGVGCH 150
            | |.|:.||.:| ||:....| |.:.:.|:.:...    ||.      :.:|.|.|:..
Mouse    66 VHQGFQLLLHNLNKQNNQKYC-LTMANRLFVENTCELLPTFKESCLKFYHSEMEQLSFA------ 123

  Fly   151 RLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTE 215
                |:|..:.|.||.....::|..:.:|:|...:.|    .|..:..:.:.|...|...|:...
Mouse   124 ----EAAEESRQHINMWVSKQTNGKIPDLLSKDSVNS----QTRLILANALYFHGTWCKRFEKNR 180

  Fly   216 TQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLER 280
            |:.:.|.......|.|..|:.:....:|.|..:.||::.:|:...||..:::.|:....::::|.
Mouse   181 TKEMPFKINKKETRPVQMMWREDTLFHAYVKEIQAQVLVMPYEGIDLNFVVLLPDEGVDISKVEN 245

  Fly   281 KLAQSDLHQLRSQ--LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFT-SEVHLSEVFSSILS 342
            .|....|......  :...:..:..||.::....|:..:|:.||:..:|. |:..|    |.:.:
Mouse   246 NLTFEKLTAWTKPEFMNRTEFHVYYPKFQLQEDYDMNSLLQHLGILNVFDGSKADL----SGMST 306

  Fly   343 SSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALP----LVINHPFFYAIGNGKT--LLLS 401
            .....|...|...::|:.|:|..|..:.:...:|..:.|    ...:|||.:.|.:..|  :|..
Mouse   307 KENLCLSEFVHKCVVEVNEEGTEAAAASAVEFIFLCSGPDPETFCADHPFLFFIMHSTTNSILFC 371

  Fly   402 G 402
            |
Mouse   372 G 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	87/389 (22%)
Serpinb9h	NP_001357856.1	serpinB	7..374	CDD:381072	87/389 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920