Protein Alignment Spn43Ad and SERPINA10

DIOPT Version :10

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 80/388 - (20%)
• Similarity: 170/388 - (43%)
• Gaps: 23/388 - (5%)

  Fly    26 LLARSPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTH 90
            :.:|...:..::.||..|..|:.: :.|.|:|.||..:..|::.|...::....:|:::.|.|..
Human   109 MASRQQLAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 172

  Fly    91 ASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAAR-MGVGCHRLSW 154
            ....|..:  ..:|...|:::.:....|.|....:|.....|:.:..|..|:.| ....|..:::
Human   173 LKPTKPGL--LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNF 235

  Fly   155 ESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSI 219
            .:||.|.:.:|: ::::.  :.|::   |:|.......|..:.|..:.|:..|...|||..|:..
Human   236 RNASQAKRLMNH-YINKE--TRGKI---PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVD 294

  Fly   220 NFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKLAQ 284
            .|.....:...|..|:|..::...........::::|:......::::.....|.|| ||..|..
Human   295 TFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTT 358

  Fly   285 SDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPL- 348
            ..:......::.|.:.:..||.::....::..:|.::|:.::|:....|||     ||::...|
Human   359 DLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSE-----LSATGRNLQ 418

  Fly   349 -GAVVQSGLLELQEDGGNADDSFSFGDLFRRALPLVI--NHPFFYAI--GNGKTLLLSGHIVD 406
             ..|:|..::|:.|.|..|.... ..::...::|.||  :.||.:.|  .....||..|.:|:
Human   419 VSRVLQRTVIEVDERGTEAVAGI-LSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVN 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	serpin42Dd-like_insects	34..407	CDD:381070	79/380 (21%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	80/388 (21%)