DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	399	Identity:	92/399 - (23%)
Similarity:	181/399 - (45%)	Gaps:	49/399 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSL--LYAESSSE--------YGSQLRQALE 87
            |.::.:|.|.|..|:.......||..||:.|.:||::  |.|:.::.        :.||..|.:|
Zfish     5 SAANTQFSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAHQPVE 69

  Fly    88 LTHASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAAR-MGVGCHR 151
            ..|:        :|:..:::|.:..| ...|.|.:.||.:|  |:....:|.....| ...|..:
Zfish    70 QIHS--------NFKKFMSELNKPEA-PYVLSLANRLYGEQ--TYQLIEKFLNDTKRYYDAGLEK 123

  Fly   152 LSWESASNAAQ-DINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTE 215
            :.:.:.|..|: :||......:...:.:|:.:..::::    |..:.|:.:.|:..|...|....
Zfish   124 VDFINKSEDARVNINTWVEKNTQEKIKDLLPSGAIDAM----TRLVLVNAIYFKGNWEEKFPKEA 184

  Fly   216 TQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPD----GLA 276
            |:...|....|:.:.|..|..:..:....:..:.:.::|:|:|..:|.|||:.|:..:    ||.
Zfish   185 TRDGVFRLNKNQTKPVKMMHQKAEFPSGYIEEMKSHVLELPYAGKNLSMLIILPDEIEDETTGLQ 249

  Fly   277 QLERKLAQSDLHQLRSQ--LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLF-TSEVHLSEVFS 338
            :|||.|....|.:....  :.:|:|.::|||.:.....|:|.:|..:|:..:| ..:|:|:.:.|
Zfish   250 KLERALTYEKLMEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSS 314

  Fly   339 S---ILSSSAPPLGAVVQSGLLELQEDGGN-ADDSFSFGDLFRRALPLVIN--HPFFYAIGNG-- 395
            |   :||.:       :....:|:.|:|.. |..:.:...|.....||..|  |||.:.|.:.
Zfish   315 SNDLVLSKA-------IHKAFVEVNEEGTEAAAATAAIEKLMCYIPPLSFNADHPFLFFIRHNPT 372

  Fly   396 KTLLLSGHI 404
            |::|..|.:
Zfish   373 KSILFYGRL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	91/395 (23%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	92/399 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920