DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinf1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001004539.1	Gene:	serpinf1 / 447800	ZFINID:	ZDB-GENE-040912-2	Length:	406	Species:	Danio rerio

Alignment Length:	442	Identity:	102/442 - (23%)
Similarity:	174/442 - (39%)	Gaps:	89/442 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WRLLSALLVGLAIALTLPVDGELLA-------RSPASVSSNRFGLRLTTKLGLTQPDANVVVSPL 61
            |.|||  |....:|.|...:||..|       |:..:.:::.||..|..:|......|:|.:||:
Zfish    11 WSLLS--LSHAQLADTTDAEGEEEAVDLFTTPRTKLAAATSDFGYNLFRQLASRDTKASVFLSPM 73

  Fly    62 LIQAALSLLYAESSSEYGSQLRQALELTHASHPKLAVQDFETLLTDLKQSAAIGCRLR-LLSDLY 125
            .|.||.:.|...:|.....|:.:||.             :.||     |.:.:...|| |||.|.
Zfish    74 SISAAFTQLSMGASERAEKQIYRALR-------------YHTL-----QDSQLHDTLRDLLSSLR 120

  Fly   126 AQQRFTFNFRNEFETLAARMGVGCHRLSWESASN--------------AAQD---INYAFLSRSN 173
            |..:   .|::....|.||.    .||..|..::              .|:|   :|..|..::.
Zfish   121 ASAK---GFKSAERILLARK----LRLRLEYLNSVEKQYGERPQILAGGARDLKTVNDWFKQQTG 178

  Fly   174 FSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAF-DPTETQSINFFAGGNRPRLVDAMFGQ 237
            ..:.::|.:|     ...||..|.|....|:..|...| .|.:.::  |...|..|.::..|
Zfish   179 GKVDQVVPSP-----LPRNTALLPVGSAYFKGKWITRFGKPNKMET--FRRDGQAPAVIPMM--- 233

  Fly   238 HRYRYAEVPALDAQL----IEVPFATADLRMLIVFPNR-PDGLAQLERKLAQSDLHQLRSQLEER 297
            .:..|.....:|:.|    .:||.... :.|....|:. ...|..:|..|....:..|.:.|...
Zfish   234 EQENYPVKMGIDSDLGCTIAQVPMEDG-VSMYFFLPDEVTQNLTLIEEALTAEFVQDLSNSLHTV 297

  Fly   298 KVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQED 362
            ||.||||.:::...::|...|.:|||:: :.:|..|:::     :|....|.||....:||...:
Zfish   298 KVLLTLPVIKLSYKTNLLPSLSDLGLSE-WLAETDLTKI-----TSQPVKLNAVHHKVVLETAPE 356

  Fly   363 GGN------ADDSFSFGDLFRRALPLVINHPFFYAIGN--GKTLLLSGHIVD 406
            |..      :....|.|..:|      ::.||.:.:.:  ...||..|.:::
Zfish   357 GAEYASTTPSATGQSLGLSYR------VDRPFLFLVRDEPSGALLFIGKVLN 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	91/400 (23%)
serpinf1	NP_001004539.1	SERPIN	30..403	CDD:294093	94/421 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100