DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn43Ad and Serpinb3d

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_958764.1	Gene:	Serpinb3d / 394252	MGIID:	2683295	Length:	387	Species:	Mus musculus

Alignment Length:	400	Identity:	91/400 - (22%)
Similarity:	180/400 - (45%)	Gaps:	48/400 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQAL----------E 87
            :|::.:|.|.|..:  |.:.|.|:..||:.:...|::|...:.:....|:::.|          |
Mouse     5 AVATTKFTLELYRQ--LRESDNNIFYSPISMMRTLAMLLLGAKANTEQQIKKVLHFNETTKKTTE 67

  Fly    88 LTHASHPKLAV-QDFETLLTDL-KQSAAIGCRLRLLSDLYAQQRFTF------NFRNEFETLAAR 144
            .:..||.:..| |.|:.|:|.| |.:.|..  |::.:.:|..:.|.|      :.|..::.....
Mouse    68 KSAESHDEENVHQQFQMLMTQLNKFNNAYD--LKVPNSIYGAKDFPFLQTFLKDIRKYYQANVES 130

  Fly   145 MGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAW 209
            :...      .:|..:.:.||.....::|..:.:|..:..|.|    :|..:.|:.|.|:..|..
Mouse   131 LDFA------HAAEESQKKINSWMARQTNGKIKDLFPSGSLNS----STILVLVNAVYFKGQWNH 185

  Fly   210 AFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDG 274
            .||...|:...|:...|..:.|..|..::::.:..:..:.|:::|:|:...:|.|.::.|...||
Mouse   186 KFDEKHTREEKFWLNKNTSKPVQMMKQRNKFNFIFLENVQAKIVEIPYKGKELSMFVLLPVEIDG 250

  Fly   275 LAQLERKLAQSDLHQ-LRSQ-LEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVF 337
            |.:.|.:|....|.| .|:: :...::.|:||:.:|....||:..||.:|:...|..:   ...|
Mouse   251 LKKFEEQLTADKLLQWTRAENMHMTELYLSLPQFKVEEKYDLRVPLEHMGMVDAFDPQ---KADF 312

  Fly   338 SSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALPL------VINHPFFYAIGNGK 396
            |.:.:|....:..|:....:|:.|:|..|..:.|   :..|:|.:      ..||||.:.:...|
Mouse   313 SGMSNSQGLVVSKVLHKSFVEVNEEGAEAATAMS---VESRSLSVPKPNDFSCNHPFLFVMKQNK 374

  Fly   397 T--LLLSGHI 404
            |  :|..|.:
Mouse   375 TNSILFFGRV 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	90/396 (23%)
Serpinb3d	NP_958764.1	SERPIN	7..387	CDD:294093	90/397 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920