Protein Alignment Spn43Ad and SERPINA2

DIOPT Version :9

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 99/453 - (21%)
• Similarity: 168/453 - (37%)
• Gaps: 88/453 - (19%)

  Fly     2 IHWRLLSALLVGLAIALTLPV--------------------DGELLARSPASVSSNRFGLRLTTK 46
            :.|.:|  ||.||...:...:                    |.|.||....|.:.......|..:
Human     5 VSWGIL--LLAGLCCLVPSSLVEDPQEDAAQKTDTSHHDQGDWEDLACQKISYNVTDLAFDLYKE 67

  Fly    47 LGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKLAVQD-FETLLTDLKQ 110
            |......:||:|:|..:..|.::|...:.::..:::.:.|.:.....|:..:.: |:.:|..|.:
Human    68 LADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVLQALSR 132

  Fly   111 -----------SAAIGCRLRL----LSD---LYAQQRFTFNFRNEFETLAARMGVGCHRLSWESA 157
                       |..:...::|    |.|   ||..:..:.|||:..|
Human   133 PDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEE------------------ 179

  Fly   158 SNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFF 222
              |.:.||.....|:...:.:||..      .:.:|....|..::|...|...|.........|.
Human   180 --AKEQINNYVEKRTGRKVVDLVKH------LKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFH 236

  Fly   223 AGGN---RPRLVDAM--FGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKL 282
            ....   |..:::.:  |..||.|  |:.:.......|..|||    ..:.|: |..:.|||.||
Human   237 VDDKTIIRVPMINHLGRFDIHRDR--ELSSWVLAQHYVGNATA----FFILPD-PKKMWQLEEKL 294

  Fly   283 AQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAP- 346
            ..|.|..::...:.|.:.|..|||.:.....||.||..||:.|:|::|..||.|     |..||
Human   295 TYSHLENIQRAFDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGV-----SQEAPL 354

  Fly   347 PLGAVVQSGLLELQEDGGNADDSFSFGD-LFRRALPLVINHPFFYAIGNGKT--LLLSGHIVD 406
            .|...|...:|.:.|.|..|..:....: .:.:...::.|.||...|.:..|  .|..|.:|:
Human   355 KLSKAVHVAVLTIDEKGTEATGAPHLEEKAWSKYQTVMFNRPFLVIIKDDITNFPLFIGKVVN 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	87/396 (22%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	88/394 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010