DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinb6b

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_038951899.1	Gene:	Serpinb6b / 364705	RGDID:	1310452	Length:	388	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	97/396 - (24%)
Similarity:	179/396 - (45%)	Gaps:	51/396 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHAS--- 92
            |...::..|...|...|| .....||:.|||.|.:.|::::..:......|:.|||.|...|
  Rat     3 PLLEANGTFAFNLLKTLG-EDSSKNVLFSPLSISSGLAMVFMGAKGTTAHQMIQALSLDKCSGRG 66

  Fly    93 ----HPKLAVQDFETLLTDLKQSAAIGCR--LRLLSDLYAQQRFTF--NFRN--------EFETL 141
                |     |.|::||..:.::   |.:  |:..:.|:.::.|..  :|::        |.|.|
  Rat    67 SRDVH-----QGFQSLLAKVNKT---GTQYLLKTANRLFGEKTFDILASFKDACRKFYEAEMEEL 123

  Fly   142 -------AARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVS 199
                   .:|.    |..:|.:.....|.|:..:.|:...:  ||:|:..:.:    |||.:.|:
  Rat   124 DFKGAPEQSRQ----HINTWVAKKTEGQSISLNWNSQKKIT--ELLSSGSVNA----NTPLVLVN 178

  Fly   200 GVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRM 264
            .:.|:..|...|:..:||.:.|....|..:.|..||.:..::...|..:...::.:|:...:|.|
  Rat   179 AIYFKGNWKKQFNKEDTQEMPFKVTKNEEKPVKMMFKKSTFKMTYVEEISTTILLLPYVGNELNM 243

  Fly   265 LIVFPNRPDGLAQLERKLAQSDLHQLRS--QLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLF 327
            :|:.|:....|..:|:::......:..|  ::|||:|.:.|||.::..:.|:|.||..||:...|
  Rat   244 IIMLPDEHIELRMVEKEITYKKFIEWTSLDKMEEREVEVFLPKFKLEENHDMKDVLHRLGMTDAF 308

  Fly   328 TSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALP-LVINHPFFYA 391
              |..::: ||.|.|.....|..|:....:|:.|:|..|..:.:....||..:| ...||||.:.
  Rat   309 --EQGMAD-FSGIASKEGLFLSKVIHKSFVEVNEEGTEAAAATAANVTFRCMVPYFCANHPFLFF 370

  Fly   392 IGNGKT 397
            |.:.:|
  Rat   371 IQHSRT 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	96/392 (24%)
Serpinb6b	XP_038951899.1	serpin	1..388	CDD:422956	97/396 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920