DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinb1l4

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_956235.2	Gene:	serpinb1l4 / 335229	ZFINID:	ZDB-GENE-030131-7169	Length:	433	Species:	Danio rerio

Alignment Length:	430	Identity:	90/430 - (20%)
Similarity:	183/430 - (42%)	Gaps:	78/430 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTH------- 90
            |.::.:|.|.|..|:.......||..||:.|.:||:::...:......|:.:.|...:
Zfish     5 SAANTQFSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNPPKPGGA 69

  Fly    91 ------------------ASHPKLAVQ------------------------------DFETLLTD 107
                              :.|...|:|                              .|..|:::
Zfish    70 TPTPAQATQKPKWTCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFNKLMSE 134

  Fly   108 LKQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAAR-MGVGCHRLSWESASNAA-QDINYAFLS 170
            |.:..| ...|.|.:.||.:|  |:.|..::.:.|.: ...|..::.:::.|.|: .:||.....
Zfish   135 LNKPGA-PYVLSLANRLYGEQ--TYQFLEKYLSDAKKYYAAGLEKVDFKNKSEASCVNINKWVEK 196

  Fly   171 RSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMF 235
            .:...:.:|:.:..::::    |..:.|:.:.|:..|...|....|:...|....|:.:.|..|.
Zfish   197 NTQEKIKDLLPSGAIDAM----TRLVLVNAIYFKGNWEKKFPKEATKDGQFKLNKNQTKPVKMMH 257

  Fly   236 GQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPD----GLAQLERKLAQSDLHQLRSQLEE 296
            .:.::.:..:|.:::|::|:|:...:|.|||:.|:..:    ||.:|||.|....|.|....:.:
Zfish   258 QKAQFPFVVIPEINSQILELPYVGKNLSMLIILPDEIEDATTGLQKLERALTYEKLMQWTKVMRQ 322

  Fly   297 RKVALTLPKLRVLVHSDLKHVLEELGLAKLF-TSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQ 360
            ::|.::|||.:.....|:|.:|..:|:..:| ..:|:|    :.:.||:...|..|:....:|:.
Zfish   323 QEVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNL----TGMSSSNDLVLSKVIHKAFVEVN 383

  Fly   361 EDGGNADDSFSFGDLFR-RALPLVIN--HPFFYAIGNGKT 397
            |:|..|  :.:.|.:.. |.|..:.|  |||.:.|.:..|
Zfish   384 EEGTEA--AAATGAVVSIRTLAQIFNADHPFLFFIRHNST 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	89/428 (21%)
serpinb1l4	NP_956235.2	SERPIN	4..433	CDD:294093	90/430 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920