DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinb1l3

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_005174262.1	Gene:	serpinb1l3 / 335119	ZFINID:	ZDB-GENE-030131-7059	Length:	415	Species:	Danio rerio

Alignment Length:	401	Identity:	116/401 - (28%)
Similarity:	183/401 - (45%)	Gaps:	28/401 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TLPVDGELLAR-SPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQL 82
            |.|.:....:| .|.|.:..||.|.|..|:.......||..|||.|.||||:|...::.....|:
Zfish    25 TPPTEDSCSSRMEPLSAAHARFCLSLFQKISDGDSSQNVFFSPLSISAALSMLSLGAAGNTKDQM 89

  Fly    83 RQALELTHASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQ--RFTFNFRNEFETLAARM 145
            .|.|....|.....|  .|..|||::.::.| ...|.|.|.||.:|  ||...|.::...|   .
Zfish    90 SQTLHFDGAESQIHA--GFTKLLTEMNRAGA-PHTLSLASRLYGEQSCRFQETFLSDTRRL---Y 148

  Fly   146 GVGCHRLSWESASNAAQD-INYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAW 209
            |.....|.:.|...|::. ||.....:::..:.:|::...::||:.    .:.|:.|.|::.|..
Zfish   149 GAELQPLDFISQPEASRGIINRWVEQQTHEKIRDLLAEGSVDSLSR----LVLVNAVYFKSSWER 209

  Fly   210 AFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPD- 273
            .|....|....|....|..:.|..||.:.|:..|.:|.::.|::|:|:|..:|.||::.||..:
Zfish   210 KFLEEHTHEQQFRTSRNESKPVQMMFQKGRFPLAFIPDVNCQILELPYAGKELSMLVLLPNAMED 274

  Fly   274 ---GLAQLERKLAQSDLHQ-LRS-QLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHL 333
               ||.:|||.|....|.. .|| .::..:|.::||:|||....:||.:|.|||:...|..:
Zfish   275 DGTGLEKLERALTLETLTDWTRSDMMDVLEVEVSLPRLRVEERLELKPLLVELGMPDAFDPQ--- 336

  Fly   334 SEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFR---RALPLVINHPFFYAIGNG 395
            ...||.:.:.....|..||....||:.|:|..|..:.:...:.|   ||.....:|||...|.:.
Zfish   337 RADFSGVCAGGELLLSTVVHQSFLEVNEEGTEAAAATAAVMMTRCLMRAERFCADHPFLMLIRHN 401

  Fly   396 KT--LLLSGHI 404
            .|  ||..|.:
Zfish   402 PTGSLLFYGRV 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	111/382 (29%)
serpinb1l3	XP_005174262.1	SERPIN	39..415	CDD:294093	112/387 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920