DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and serpinc1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_878283.1	Gene:	serpinc1 / 321545	ZFINID:	ZDB-GENE-030131-264	Length:	450	Species:	Danio rerio

Alignment Length:	450	Identity:	95/450 - (21%)
Similarity:	176/450 - (39%)	Gaps:	99/450 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LPVDGELLARSPASVSSN----------------------RFGLRLTTKLGLTQP-DANVVVSPL 61
            ||::...:.|:|..:..|                      ||.|.|..:|...:. |.|:.:||:
Zfish    32 LPLEPMCIYRNPDEIQPNKEPENIPVGTNPRVWELSKANSRFALSLFKQLAEGKSNDENIFLSPI 96

  Fly    62 LIQAALSLLYAESSSEYGSQLRQALELTHASHPKLAVQDFETLLTDLKQS-----AAIGCRL--- 118
            .|..|.::....:.:....||             :.|..|:|:.......     |.:.|||
Zfish    97 SISTAFAMTKLGACNTTLEQL-------------MKVFQFDTIKEKTSDQVHFFFAKLNCRLYRK 148

  Fly   119 -----RLLS--DLYAQQRFTFN--FRNEFETLAARMGVGCHRLSWESASNAAQ-DINYAFLSRSN 173
                 .|:|  .|:..:..|||  |::..||:   .|.....|.::....|:: .||....:::.
Zfish   149 KHETTELISANRLFGDKSTTFNETFQHISETV---YGAKLMPLDFKEKPEASRITINEWIANKTE 210

  Fly   174 FSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQH 238
            ..:.:.:.    |...:.||..:.|:.:.|:..|...||......::|.........|..|:.:.
Zfish   211 NRIKDTLP----EGSIDTNTILVLVNAIYFKGQWKNKFDKQNVMKLDFHVSPTHKCPVPMMYQEK 271

  Fly   239 RYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKLAQSDLHQLRSQL---EERKVA 300
            :::||::|....:::|:|:...|:.|:::.|  .:| |.|...:|..:|.:|...|   :|..||
Zfish   272 KFQYAKIPEDKVKILELPYNGGDITMVLILP--IEG-ATLSEVVANMNLKKLVGWLHAMKETTVA 333

  Fly   301 LTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGA-----------VVQS 354
            :.:|:.||.....||..|.::||..||           |..::|.|.:.|           ....
Zfish   334 VQIPRFRVEDSFSLKEQLTKMGLEDLF-----------SPANASLPGMVADAEGPNLFISDAYHK 387

  Fly   355 GLLELQEDGGNADDSFSFG------DLFRRALPLVINHPFFYAIGNG--KTLLLSGHIVD 406
            ..||:.|:|..|..:.:..      ::||.  ..|.:.||...|...  ..|:.:|.:.:
Zfish   388 AFLEVNEEGSEASAATAVVATGRSLNIFRE--QFVADRPFLLFIRESSINALIFTGRVAN 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	91/431 (21%)
serpinc1	NP_878283.1	antithrombin-III_like	62..443	CDD:239000	90/416 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020