DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinb12

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_038946584.1	Gene:	Serpinb12 / 304692	RGDID:	1566382	Length:	423	Species:	Rattus norvegicus

Alignment Length:	432	Identity:	92/432 - (21%)
Similarity:	171/432 - (39%)	Gaps:	80/432 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQAL--------ELTHA 91
            ::|:|......::.......|:.|.||.:.||..::...:..:...|:.:.|        |....
  Rat     7 ANNKFCFDFFQEISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAQQIDEVLHFNELPKDERKEP 71

  Fly    92 SHPKLAVQDFETLLTDLKQSAA----------------IGCR----------------LRLLSDL 124
            |.|....:..::.|...||:.|                :||.                |.:.:.|
  Rat    72 SEPSSKSKASDSSLEGQKQTTASQGQQVSGESTNEHRLLGCHFGKLLSRIDRDKAHYTLSMANRL 136

  Fly   125 YAQQRF----------TFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGEL 179
            |.:|.|          |..:....|::..:          :....:.::||:...|:|...:.||
  Rat   137 YGEQEFPICPEYSDDITEFYHTTIESVDFQ----------KDTEKSREEINFWVESQSQGKIKEL 191

  Fly   180 VSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAE 244
            ..    :...:::|..:.|:.|.|:|.|...||...|....|....|..:.|..|..:.::|...
  Rat   192 FD----KEAIDNSTVLVLVNAVYFKAKWEKEFDSENTVDAPFCLSENEKKTVKMMNQKGQFRIGF 252

  Fly   245 VPALDAQLIEVPFATADLRMLIVFPNRPD----GLAQLERKLAQSDLHQLRS--QLEERKVALTL 303
            :..|.||::|:.:.|..|.||::.|:..:    .|.:||:|:....|....:  .:.|:.||::.
  Rat   253 IEELQAQILEMKYTTGKLSMLVLLPSSSEDNVKSLQELEKKINHEKLLAWSNPENMSEKPVAISF 317

  Fly   304 PKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADD 368
            |:..:....||..||:::|:..:|..   .....:.|..|.:..|..||....:|:.|.|..| .
  Rat   318 PQFIMEDSYDLNSVLQDMGIRDVFDG---TKADLTGISKSPSLHLSKVVHKTFVEVDEMGTQA-A 378

  Fly   369 SFSFGDLFRRALPLVI----NHPF-FYAIGNG-KTLLLSGHI 404
            :.|...:..:|||..:    |.|| |:...|| ::||..|.:
  Rat   379 AASGAVVAEKALPSRVEFNANRPFLFFIRHNGTQSLLFCGRV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	92/430 (21%)
Serpinb12	XP_038946584.1	serpinB12_yukopin	1..423	CDD:381037	92/432 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920