DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpina6

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001009663.1	Gene:	Serpina6 / 299270	RGDID:	1595901	Length:	396	Species:	Rattus norvegicus

Alignment Length:	396	Identity:	96/396 - (24%)
Similarity:	159/396 - (40%)	Gaps:	56/396 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LTLPVDGELLARSPASVSSNR----------FGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYA 72
            |.|...|...|::..:.|||.          |...|..:|....||.|.::||:.|..||:::
  Rat    10 LWLCTSGLWTAQASTNESSNSHRGLAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMV-- 72

  Fly    73 ESSSEYGSQLRQALE-----LTHASHPKLAVQDFETLLTDLKQSAA-----IGCRLRLLSDLYAQ 127
                ..||...|:|:     ||..|..::. |.|:.|...||||..     :|..:.||..|..:
  Rat    73 ----SLGSAQTQSLQSLGFNLTETSEAEIH-QSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLK 132

  Fly   128 QRFTFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHN 192
            ..|..:.:..:|:.|.       .:.:|..:.|:|.||.....::...:..:.|  .|:|.|.
  Rat   133 DSFLADVKQYYESEAL-------AIDFEDWTKASQQINQHVKDKTQGKIEHVFS--DLDSPAS-- 186

  Fly   193 TPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPF 257
              |:.|:.:..|..|...|.|..|:..:|:........|..|.......|........|||::.:
  Rat   187 --FILVNYIFLRGIWELPFSPENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDY 249

  Fly   258 ATADLRMLIVFPNRPDGLAQLE---RKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLE 319
            ........|:    || ..|::   ..|::..:.:....:..|:|.|.:||..:....|||.:||
  Rat   250 VGNGTAFFIL----PD-QGQMDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSISDTYDLKDMLE 309

  Fly   320 ELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALPLVI 384
            :|.:..|.|::...|.     .:...|....:|...:|:|.| |....:|.:...|..|:.||.|
  Rat   310 DLNIKDLLTNQSDFSG-----NTKDVPLTLTMVHKAMLQLDE-GNVLPNSTNGAPLHLRSEPLDI 368

  Fly   385 --NHPF 388
              |.||
  Rat   369 KFNKPF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	92/379 (24%)
Serpina6	NP_001009663.1	alpha-1-antitrypsin_like	37..392	CDD:239011	89/369 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110