DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	88/401 - (21%)
Similarity:	159/401 - (39%)	Gaps:	74/401 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHAS-------HPKL 96
            |.|:|...|. .....|:.:||:.|.|||::::..:.....||:.|.|.|...|       |
  Rat    32 FALKLLKTLS-EDSSNNIFLSPISISAALTMVFMGAKGMTASQMVQTLSLDKCSGNGGGDVH--- 92

  Fly    97 AVQDFETLLT-----------------------DLKQSAAIGCRLRLLSDLYAQQRFTFNFRNEF 138
              |.|::||.                       |:..|....||     ..|..:....:|:.:.
  Rat    93 --QGFQSLLAEVNKTGTQYLLKTANRLFGEKTCDILASFKDACR-----KFYEAEMEELDFKGDT 150

  Fly   139 ETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTF 203
            |                   .:.|.||.....::...:.||: ||   .:.:.:|..:.|:.:.|
  Rat   151 E-------------------QSRQRINTWVAKKTEDKIKELL-AP---GIVDPDTVLVLVNAIYF 192

  Fly   204 RAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVF 268
            :..|...|:...|:...|.......:.|..||.:..::...:..:..:::.:|:|..:|.|:|:.
  Rat   193 KGNWDKQFNKEHTREKPFKVSKTEEKPVQMMFMKSTFKMTYIGEIFTKILLLPYAGNELNMIIML 257

  Fly   269 PNRPDGLAQLERKLAQSDLHQLR--SQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEV 331
            |:....|..:|::|......:..  ..|:|.:|.:.||:.::..:.|:|.||.:||:...|   :
  Rat   258 PDEHIELKTVEKELTYEKFIEWTRLDMLDEEEVEVFLPRFKLEENYDMKVVLGKLGMTDAF---M 319

  Fly   332 HLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFR--RALP-LVINHPFFYAIG 393
            .....||.|.|.....|..|:....:|:.|:|..|..:.......|  |..| .:.:|||.:.|.
  Rat   320 EGRADFSGIASKQGLFLSKVIHKAFVEVNEEGTEAVAATGSTITMRCLRFTPRFLADHPFLFFIQ 384

  Fly   394 NGKT--LLLSG 402
            :.||  :|..|
  Rat   385 HVKTKGILFCG 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	88/401 (22%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	88/401 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920