DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpina4

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_659565.2	Gene:	Serpina4 / 246328	RGDID:	708581	Length:	423	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	81/395 - (20%)
Similarity:	157/395 - (39%)	Gaps:	43/395 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQAL--ELTHASHP 94
            ||.::| |..||...:.....:.|:..|||.|..:|::|...:..:..:|:.:.|  .||..|.|
  Rat    49 ASGNAN-FAFRLYHLIASQNSEKNIFFSPLSISVSLAILSTGAGGDTQAQILEGLGFNLTKLSLP 112

  Fly    95 KLAVQDFETLLTDL-----KQSAAIGCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRLSW 154
            ::. :.|.:|...:     :...::|..|.|..:|.....|.......:.:...       ..::
  Rat   113 EIH-EGFRSLQHTIARPFTEPQISVGSALILSQNLQILSEFVSAIETSYNSKVL-------HANF 169

  Fly   155 ESASNAAQDINYAFLSRSNFSLGELVS--APQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQ 217
            .....|.|.||......:...:..|||  :|.::.:.        |:.:.|:..|...|..:...
  Rat   170 RDKEAAVQLINNYVKQNTQGKIKNLVSDLSPDVKMVL--------VNYIFFQGLWKKPFPSSRVS 226

  Fly   218 SINFFAGGNRPRLVDAMF-GQHRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERK 281
            :.:|:...|....:..|. .:..:.|.|...:...::.:.: ..|.....:.|:: ..:.::|:.
  Rat   227 TSDFYVDENTVVKIPMMLQDKEDHWYLEDRRVPCTVLRMDY-RGDAVAFFILPDQ-GKMNEVEQV 289

  Fly   282 LAQSDLHQLRSQLEE----RKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILS 342
            |:...|.:.:..|:.    ||:.|.|||..:....:|..:|.:||...|||...:    ||:|..
  Rat   290 LSPGMLLRWKRLLQNRFFYRKLILQLPKFSISNSYELDEILPDLGFQDLFTPNAN----FSNISK 350

  Fly   343 SSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALP----LVINHPFFYAI--GNGKTLLLS 401
            .....|..|....:|::.|.|..|..:......|..|.|    |:.|.||...:  .:.:.:|..
  Rat   351 KEKLYLSKVFHKTVLDVNEVGTKAAAATGSFATFFSAQPKKRYLIFNRPFLVILYSTSSQDILFM 415

  Fly   402 GHIVD 406
            |.:|:
  Rat   416 GKVVN 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	78/388 (20%)
Serpina4	NP_659565.2	SERPIN	52..418	CDD:294093	78/388 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110