DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpine1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_036752.2	Gene:	Serpine1 / 24617	RGDID:	3249	Length:	402	Species:	Rattus norvegicus

Alignment Length:	422	Identity:	85/422 - (20%)
Similarity:	163/422 - (38%)	Gaps:	45/422 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSALLVGLAIALTLPVDGE----LLARSPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAAL 67
            :|:.|..|.:.|.| |.|:    .|..|..:..:..||:::...:.....|.|||.||..:.:.|
  Rat     3 MSSALTCLTLGLVL-VFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVL 66

  Fly    68 SLLYAESSSEYGSQLRQALELT---HASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQR 129
            ::|...::.:...|::.|:...   ..:.|.|.....|.:.:..|...:....:.:..||...|.
  Rat    67 AMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQG 131

  Fly   130 FTFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGE--------LVSAPQLE 186
            |..:|...|.|                   ..:.::::.:.|:.|.:.:        ::|....:
  Rat   132 FMPHFFKLFRT-------------------TVKQVDFSEMERARFIINDWVERHTKGMISDLLAK 177

  Fly   187 SLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDA- 250
            ......|..:.|:.:.|...|...|....|....|.........|..|...:::.|.|....|.
  Rat   178 GAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGH 242

  Fly   251 --QLIEVPFATADLRMLIVFPNRPD-GLAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLVHS 312
              .::|:|:....|.|.|..|...| .|:.:...|....:.|.:|.:......|.|||..:....
  Rat   243 EYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSLETEV 307

  Fly   313 DLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFR 377
            ||:..||:||:..:|:|   ....|:|:.......:...:|...:|:.|.|..|..|.:.....|
  Rat   308 DLRGPLEKLGMTDIFSS---TQADFTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILVSAR 369

  Fly   378 RA-LPLVINHPFFYAIGNG--KTLLLSGHIVD 406
            .| ..:|::..|.:.:.:.  :|:|..|.:::
  Rat   370 MAPTEMVLDRSFLFVVRHNPTETILFMGQLME 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	76/386 (20%)
Serpine1	NP_036752.2	serpin	29..402	CDD:422956	77/395 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020