DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001157589.1	Gene:	Serpinb6a / 20719	MGIID:	103123	Length:	399	Species:	Mus musculus

Alignment Length:	402	Identity:	88/402 - (21%)
Similarity:	173/402 - (43%)	Gaps:	51/402 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLARSPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTH 90
            |....|...::..|.|.|...|| .....||.:||:.|.:||::::..:.....||:.|||.|..
Mouse    19 LTIMDPLQEANGTFALNLLKILG-EDSSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDK 82

  Fly    91 AS-------HPKLAVQDFETLLTDLKQSAA---IGCRLRLLSDLYAQQRFTFN------FRNEFE 139
            .|       |     |.|::|||::.::..   :....||..|.......:|.      :..|.|
Mouse    83 CSGNGGGDVH-----QGFQSLLTEVNKTGTQYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELE 142

  Fly   140 TLAARMGVGCHRLSWESAS-NAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTF 203
                       .|.::.|: .:.|.||.....::...:.|::|...:.|    :|..:.|:.:.|
Mouse   143 -----------ELDFQGATEESRQHINTWVAKKTEDKIKEVLSPGTVNS----DTSLVLVNAIYF 192

  Fly   204 RAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATADLRMLIVF 268
            :..|...|:...|:.:.|....|..:.|..||.:..::...:..:..:::.:|:.:::|.|:|:.
Mouse   193 KGNWEKQFNKEHTREMPFKVSKNEEKPVQMMFKKSTFKMTYIGEIFTKILLLPYVSSELNMIIML 257

  Fly   269 PNRPDGLAQLERKLAQSDLHQLR--SQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEV 331
            |:....|:.:|:::......:..  .:::|.:|.:.|||.::..:.::...|.:||:...|....
Mouse   258 PDEHVELSTVEKEVTYEKFIEWTRLDKMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAFGGRA 322

  Fly   332 HLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALPLV----INHPFFYAI 392
            .    ||.:.|.....|..||....:|:.|:|..| .:.:.|.:..|.:...    .:|||.:.|
Mouse   323 D----FSGMSSKQGLFLSKVVHKAFVEVNEEGTEA-AAATAGMMTVRCMRFTPRFCADHPFLFFI 382

  Fly   393 GNGKT--LLLSG 402
            .:.||  :|..|
Mouse   383 HHVKTNGILFCG 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	86/393 (22%)
Serpinb6a	NP_001157589.1	SERPIN	25..399	CDD:294093	86/396 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920