Protein Alignment Spn43Ad and Serpina1a

DIOPT Version :10

• Sequence 1: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 435
• Identity: 92/435 - (21%)
• Similarity: 171/435 - (39%)
• Gaps: 60/435 - (13%)

  Fly     2 IHWRLLSALLVGLAIAL-------TLPVDGELLARSPAS--VSSN--RFGLRLTTKLGLTQPDAN 55
            |.|.||  ||.||...:       ....|.....:||||  :::|  .|.:.|..:|......:|
Mouse    28 ISWGLL--LLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNTSN 90

  Fly    56 VVVSPLLIQAALSLLYAESSSEYGSQLRQALE--LTHASHPKLAVQDFETLLTDLKQ-----SAA 113
            :..||:.|..|.::|...|..:..:|:.:.|:  ||..|...:. :.|:.||..|.:     ..:
Mouse    91 IFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIH-KSFQHLLQTLNRPDSELQLS 154

  Fly   114 IGCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGE 178
            .|..|.:.:||...::|....:|.::.                   ....:|:|....:...:.:
Mouse   155 TGNGLFVNNDLKLVEKFLEEAKNHYQA-------------------EVFSVNFAESEEAKKVIND 200

  Fly   179 LVSAPQLESLAE------HNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQ 237
            .|.......:||      .:|.|...:.:.|:..|...|||..|:...|....:....|..|...
Mouse   201 FVEKGTQGKIAEAVKKLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVKVPMMTLS 265

  Fly   238 HRYRYAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQ-LERKLAQSDLHQLRSQLEERKVAL 301
            ..........|.:.::.:.:| .:...:.:.|:  ||..| ||:.|::..:.:.......|...:
Mouse   266 GMLHVHHCSTLSSWVLLMDYA-GNATAVFLLPD--DGKMQHLEQTLSKELISKFLLNRRRRLAQI 327

  Fly   302 TLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAP-PLGAVVQSGLLELQEDGGN 365
            ..|:|.:....:||.::..||:.::|.:...|    |.|...:|| .|...|...:|.:.|.|..
Mouse   328 HFPRLSISGEYNLKTLMSPLGITRIFNNGADL----SGITEENAPLKLSQAVHKAVLTIDETGTE 388

  Fly   366 ADDSFSFGDLFRRALPLVI--NHPFFYAIGNGKTL--LLSGHIVD 406
            | .:.:...:...::|.::  :|||.:.|....|.  :..|.:||
Mouse   389 A-AAVTVLQMVPMSMPPILRFDHPFLFIIFEEHTQSPIFLGKVVD 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	serpin42Dd-like_insects	34..407	CDD:381070	79/394 (20%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	79/394 (20%)