DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpinf1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_035470.3	Gene:	Serpinf1 / 20317	MGIID:	108080	Length:	417	Species:	Mus musculus

Alignment Length:	391	Identity:	95/391 - (24%)
Similarity:	157/391 - (40%)	Gaps:	48/391 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKL 96
            |:||:  ||..|........|..||::|||.:..|||.|...:.....|.:.:||.....::|.:
Mouse    55 AAVSN--FGYDLYRLRSSASPTGNVLLSPLSVATALSALSLGAEHRTESVIHRALYYDLITNPDI 117

  Fly    97 AVQDFETLLT-------DLKQSAAI--GCRLRLLSDLYAQQRFTFNFRNEFETLAARMGVGCHRL 152
            . ..::.||.       :||.::.|  ..:||:.|...|....::..|       .|:..|..|:
Mouse   118 H-STYKELLASVTAPEKNLKSASRIVFERKLRVKSSFVAPLEKSYGTR-------PRILTGNPRV 174

  Fly   153 SWESASNAAQDINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVT-FRAPWAWAFDPTET 216
            ..:..:|..|......::||.   .|:.||..:..|           ||. |:..|...||..:|
Mouse   175 DLQEINNWVQAQMKGKIARST---REMPSALSILLL-----------GVAYFKGQWVTKFDSRKT 225

  Fly   217 QSINFFAGGNRPRLVDAMFGQHR-YRYAEVPALDAQLIEVPFATADLRMLIVFP-NRPDGLAQLE 279
            ...:|....:|...|..|..... .||.....|:.::.::|. |..:.::...| .....|..:|
Mouse   226 TLQDFHLDEDRTVRVPMMSDPKAILRYGLDSDLNCKIAQLPL-TGSMSIIFFLPLTVTQNLTMIE 289

  Fly   280 RKLAQSDLHQLRSQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSS 344
            ..|....:|.:..:|:..:..||:|||::....:|...|:::.|..||.     |..||.| :..
Mouse   290 ESLTSEFIHDIDRELKTIQAVLTVPKLKLSFEGELTKSLQDMKLQSLFE-----SPDFSKI-TGK 348

  Fly   345 APPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALPL--VINHPFFYAIGNGKT--LLLSGHIV 405
            ...|..|......|..|:|..:..|.....: |...||  .:|.||.:.:.:..|  ||..|.|:
Mouse   349 PVKLTQVEHRAAFEWNEEGAGSSPSPGLQPV-RLTFPLDYHLNQPFLFVLRDTDTGALLFIGRIL 412

  Fly   406 D 406
            |
Mouse   413 D 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	91/384 (24%)
Serpinf1	NP_035470.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..41
Serpinf1	NP_035470.3	PEDF	39..414	CDD:239007	95/391 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100