DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and Serpine1

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_032897.2	Gene:	Serpine1 / 18787	MGIID:	97608	Length:	402	Species:	Mus musculus

Alignment Length:	424	Identity:	87/424 - (20%)
Similarity:	170/424 - (40%)	Gaps:	53/424 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSALLVGLAI----ALTLPVDGELLARSPASVSSNRFGLRLTTKLGLTQPDANVVVSPLLIQAAL 67
            |:.|::||.:    ..|||     |..|..:..:..||:::..::.....|.|||.||..:.:.|
Mouse     7 LACLILGLVLVSGKGFTLP-----LRESHTAHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVL 66

  Fly    68 SLLYAESSSEYGSQLRQALELTHASHPKLAVQDFETLLTDL-----KQSAAIGCRLRLLSDLYAQ 127
            ::|...::.:...|::.|:..  ..:.|........|..:|     |...:....:.:..||...
Mouse    67 AMLQMTTAGKTRRQIQDAMGF--KVNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELV 129

  Fly   128 QRFTFNFRNEFETLAARMGVGCHRLSWESASNAAQDINYAFLSRSNFSLGE--------LVSAPQ 184
            |.|..:|...|:|:                   .:.::::.:.|:.|.:.:        ::|...
Mouse   130 QGFMPHFFKLFQTM-------------------VKQVDFSEVERARFIINDWVERHTKGMISDLL 175

  Fly   185 LESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEV---P 246
            .:...:..|..:.|:.:.|...|...|....|....|.........|..|...:::.|.|.   .
Mouse   176 AKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPD 240

  Fly   247 ALDAQLIEVPFATADLRMLIVFPNRPD-GLAQLERKLAQSDLHQLRSQLEERKVALTLPKLRVLV 310
            .|:..::|:|:....|.|.|..|...| .|:.|...|....:.|.:..:......|.|||..:..
Mouse   241 GLEYDVVELPYQGDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLET 305

  Fly   311 HSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDL 375
            ..||:..||:||:..:|::.  |:: |:|:.......:...:|...:|:.|.|..|..|.:|...
Mouse   306 EVDLRGPLEKLGMPDMFSAT--LAD-FTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVIS 367

  Fly   376 FRRA-LPLVINHPFFYAIGNG--KTLLLSGHIVD 406
            .|.| ..:||:..|.:.:.:.  :|:|..|.:::
Mouse   368 ARMAPTEMVIDRSFLFVVRHNPTETILFMGQVME 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	78/388 (20%)
Serpine1	NP_032897.2	SERPIN	29..402	CDD:294093	79/397 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110