DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn43Ad and srp-6

DIOPT Version :9

Sequence 1:	NP_610261.1	Gene:	Spn43Ad / 35639	FlyBaseID:	FBgn0044011	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_504890.1	Gene:	srp-6 / 179125	WormBaseID:	WBGene00005647	Length:	375	Species:	Caenorhabditis elegans

Alignment Length:	378	Identity:	95/378 - (25%)
Similarity:	160/378 - (42%)	Gaps:	31/378 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SSNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQALELTHASHPKLAVQ 99
            |...|||.|..:..||:   :.|.|||.|..||||::..:..|...::|:|| |..|:..:|. |
Worm    16 SETDFGLSLLRQQNLTE---SFVFSPLSIALALSLVHVAAKGETRDEIRKAL-LNGATDEELE-Q 75

  Fly   100 DFETLLTDLKQSAAIGCRLRLLSDLYAQQRFTFN--FRNEFETLAARMGVGCHRLSWESASNAAQ 162
            .|..:...| ..|..|..:.:.:.:::::.||..  :.|:.:.|   ...|..:|::|....:|:
Worm    76 HFSNISAGL-LVAEKGTEVNVANHIFSRKTFTIKKLYLNDVKKL---YNAGASQLNFEDQEASAE 136

  Fly   163 DINYAFLSRSNFSLGELVSAPQLESLAEHNTPFLHVSGVTFRAPWAWAFDPTETQSINFFAGGNR 227
            .|| .|:|.:  :.|.:......:|::|.....| .:...|:|.|...|....|....||:..|.
Worm   137 AIN-NFVSEN--TKGHIKKIINPDSISEELVAVL-TNAFYFKANWQTKFKKESTYKREFFSSENS 197

  Fly   228 PRLVDAMFGQHRYR-YAEVPALDAQLIEVPFATADLRMLIVFPNRPDGLAQLERKLAQSDLHQLR 291
            .|..:.:..::..| |:|....  |::.:|:......:.|..|....||::..:.|....:.||.
Worm   198 KRETEFLHSRNSNRKYSENGQF--QVLSLPYKDTSFALSIFLPKTRFGLSEALQNLDSVTIQQLM 260

  Fly   292 SQLEERKVALTLPKLRVLVHSDLKHVLEELGLAKLFTSEVHLSEVFSSILSSSAPPLGAVVQSGL 356
            |......|.:.:||.::.....|...|..:|:.|.||....||.....|..|.|      ....|
Worm   261 SNTSNTLVNIAMPKWKIETALGLNRALMAVGIEKAFTDSADLSNFADGIYISQA------AHKAL 319

  Fly   357 LELQEDGGNA----DDSFSFGDLF---RRALPLVINHPFFYAIGNGKTLLLSG 402
            :|:.|||..|    ..|||...:|   ...:....:|||.:.:......|..|
Worm   320 IEVDEDGTVAAAATTISFSLTSVFIPAEEPIEFTADHPFLFILSKDNHPLFIG 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn43Ad	NP_610261.1	SERPIN	35..404	CDD:238101	95/378 (25%)
srp-6	NP_504890.1	serpinL_nematode	16..374	CDD:381047	95/378 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020