Protein Alignment Cyp9b2 and ERG11

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 122/557 - (21%)
• Similarity: 201/557 - (36%)
• Gaps: 155/557 - (27%)

  Fly     8 LALVVIGYLIYK--WSTATFKTFEERKLYFEKP------YPFVGNMAAAALQKSSFQRQLTEFYE 64
            ::|::|...||.  |..    .:..||   ::|      .|:||:.....::...|..:..:.|.
Yeast    31 ISLIIIIPFIYNIVWQL----LYSLRK---DRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYG 88

  Fly    65 RTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLS-VMRDQRWK 128
            ......|:|    |...:.|.                |....|:      ||..|: |..:..:.
Yeast    89 DIFSFVLLG----RVMTVYLG----------------PKGHEFV------FNAKLADVSAEAAYA 127

  Fly   129 HMRNTLTPVF------------------------TAAKMRNMFTLMNESFAECLQHLDSSSKTLP 169
            |:   .||||                        |....::...|:.|...:..:  ||.:..|.
Yeast   128 HL---TTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFR--DSKNFRLN 187

  Fly   170 GRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQF-------FKF 227
            .|....:|:.|                      ..|:...:...:||:   |.:.       |.:
Yeast   188 ERTTGTIDVMV----------------------TQPEMTIFTASRSLL---GKEMRAKLDTDFAY 227

  Fly   228 MLSTL----VPKLFSLLKLTIFDSAKVDYFARLV----VEAMQYREKHN-ITRPDMIQLLMEAKN 283
            :.|.|    .|..|....|.:....|.|:..:.:    :..::.|.|:| |...|:|..||:...
Yeast   228 LYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNST 292

  Fly   284 ESED-KWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLY---NPDVQERLYEEIVETKKALNGA 344
            ..:. |.||.|| |...|......::.|  ..|:.:.||:   .||||:.|||   |..:.|:|.
Yeast   293 YKDGVKMTDQEI-ANLLIGVLMGGQHTS--AATSAWILLHLAERPDVQQELYE---EQMRVLDGG 351

  Fly   345 --PLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISG 407
              .||||.:|:|..::..|.|:||......:..|...||..:.:..    :....|..:.:....
Yeast   352 KKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTS----YVIPAGYHVLVSPGY 412

  Fly   408 LHLDDRYFPEPRKFDPDRFSEERK-----GDMVPY-----------TYLPFGVGPRNCIGNRYAL 456
            .||.|.|||...:|:..|::::..     |:.|.|           .|||||.|...|||..:|.
Yeast   413 THLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAY 477

  Fly   457 MQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTP 493
            .|: |:|.::.:        ||:|  |....|....|
Yeast   478 CQL-GVLMSIFI--------RTLK--WHYPEGKTVPP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	109/490 (22%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	110/498 (22%)