DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9b2 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	104/450 - (23%)
Similarity:	194/450 - (43%)	Gaps:	78/450 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 EFYERTRQH-----KLVG-----FFNMRTPMITLNDPELIKKVCVK--DFDHFPNHQPFITSNDR 113
            ||..|...|     ::.|     :|..: |::..:||.||::....  .||.. .|.|.   :..
plant    73 EFVHRVAPHYHEWSRVYGKTFLYWFGSK-PVVATSDPRLIREALTTGGSFDRI-GHNPL---SKL 132

  Fly   114 LFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDM 178
            |:...|..:|..:|...|......||..|::.....|..|....::..:....   |.:..|:::
plant   133 LYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQMVTSTMMLMEKWEDMRN---GGEEIELEV 194

  Fly   179 KVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSL----------VFSRGLQFFKFMLSTLV 233
            ....:.||.::::.||||   ||.:..|. .:|:.:.:          |:..|.:||....:..:
plant   195 HKEMHNLSAEMLSRTAFG---NSVEEGKG-IFELQERMMRLFYLVRWSVYIPGFRFFPSKTNREI 255

  Fly   234 PKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEA-------KNESEDKWTD 291
            .::...::::|.         :|:        ::|.|..:....|::|       :|..|:|...
plant   256 WRIEKQIRVSIL---------KLI--------ENNKTAVEKSGTLLQAFMSPYTNQNGQEEKLGI 303

  Fly   292 DEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIV----ETKKALNGAPLTYDAVQ 352
            :|:..:|..|:|||.|..:||:......|..|.:.|....||::    :|     |.| |.|.:|
plant   304 EEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEWQNIAREEVICVLGQT-----GLP-TLDILQ 362

  Fly   353 KMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLD-DRYFP 416
            .:..:.|:|:|:||.:..|...:|...|...|.|      .|...|.::.:.:..:|.| :.:..
plant   363 DLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGD------LDIPAGTQLYLSVVAMHHDKETWGD 421

  Fly   417 EPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASP 476
            :..:|:|.||.:.:|...:   .:|||:|||.|:|...|:.:.|.:|..:|.:|....||
plant   422 DAEEFNPRRFEDPKKQSAL---LVPFGLGPRTCVGQNLAVNEAKTVLATILKYYSFRLSP 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	103/449 (23%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	103/449 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900