DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b2 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	123/551 - (22%)
Similarity:	224/551 - (40%)	Gaps:	100/551 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKP-YPFVGN--------MAAAALQKSSFQRQ 58
            ::.|||..:.:....:.|.....|...........| :|| ||        ||:..:..|.....
plant    18 VVVICLMFLKLFLRCWIWPVRAQKKLRGNGFVGPAPSFPF-GNLNDMKKLKMASVVVDNSKSSTI 81

  Fly    59 LTE--------FYERTRQH--KLVGFFNMRTPMITLNDPELI----KKVCVKDFDHFPNHQPFIT 109
            :..        .:.|.:|.  |:..::....|.:.:.|||.:    |.|..|.:.     :|.:.
plant    82 INHDIHSIALPHFARWQQEYGKVFVYWLGIEPFVYVADPEFLSVMSKGVLGKSWG-----KPNVF 141

  Fly   110 SNDR--LFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRK 172
            ..||  :|...|.::....|...|:.:||.|....::.|..:|.||.:..|........:  |..
plant   142 KKDREPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMVESVSNMLDRWGIQINS--GNP 204

  Fly   173 GFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIG-QSLVFSRGLQFFKFMLSTLVPKL 236
            .|:::.:::  ..:.:|||.|:||:.           .|.| |.|...|.:||..|..:..|...
plant   205 EFDMESEII--GTAGEIIAKTSFGVT-----------GENGTQVLKNLRAVQFALFNSNRYVGVP 256

  Fly   237 FSLL---KLTI--------FDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWT 290
            ||.:   |.|:        .|...:.:..:..:...:..::.:    |::.:|::|  :.:..:|
plant   257 FSNILSYKQTVKAKGLGHEIDGLLLSFINKRKISLAEGDDQGH----DLLGMLLKA--DQKGNFT 315

  Fly   291 DDEIVAQCFIFFFAAFENNSNLICTTTYELL-YNPDVQERLYEEIVETKKALNGAPLTYDAVQKM 354
            ..|:|.:|..||||..|..: |..|.|:.|| .:|:.|:.:.|||   ::.:..:.:.|:.:..:
plant   316 AKELVDECKTFFFAGHETTA-LALTWTFMLLAIHPEWQDTIREEI---REVIGDSKIEYNKLAGL 376

  Fly   355 TYMDMVISESLRKWTLAAATDRLCSKDYTLTD---DDGTKLFDFKVGDRINIPISGLHLD-DRYF 415
            ..|..|::|.||.:..|....|....|..:..   .:||.::         |.:..:|.| :.:.
plant   377 KKMSWVMNEVLRLYPPAPNAQRQARNDIEVNGRVIPNGTNIW---------IDVVAMHHDVELWG 432

  Fly   416 PEPRKFDPDRFSEERKGDMV-PYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTI 479
            .:..:|.|:||.....|... ...|:|||.|.|.|||.....|:.|.:|..:|..::|..||
plant   433 DDVNEFKPERFDGNLHGGCKNKMGYMPFGFGGRMCIGRNLTTMEYKIVLSLVLSRFEISVSP--- 494

  Fly   480 KDLWGSASGFNFTP------RSGFWMHLVPR 504
                    |:..:|      |.|:.:.|:.|
plant   495 --------GYRHSPTYMLSLRPGYGLPLIIR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	112/483 (23%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	123/551 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810