Protein Alignment Cyp9b2 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 561
• Identity: 137/561 - (24%)
• Similarity: 240/561 - (42%)
• Gaps: 135/561 - (24%)

  Fly     1 MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYER 65
            :||: .|||||::               :..|||               |::....|.|:.| ..
Mouse    16 LALV-FCLALVLM---------------QAMKLY---------------LRRQRLLRDLSPF-PG 48

  Fly    66 TRQHKLVGF--FNMRTPMITLNDPELIKK-----VC-VKDFDHF-----PNH-QPFITSND---R 113
            ...|.|:|.  |.....|.||:  |::||     .| |..|..|     |:: :.|::..|   :
Mouse    49 PPAHWLLGHQKFLQEDNMETLD--EIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQ 111

  Fly   114 LFNDMLSV--------MRDQRWKHMRNTLTPVF----------TAA--------KMRNMFTLMNE 152
            ..:.:|:.        :...||...|..|||.|          |.|        |...|:| ..|
Mouse   112 YLHQLLTPCIGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWT-TQE 175

  Fly   153 SFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVN-----SYDNPKNEFYEI 212
            :..|..:|:                     |.::.|||...|||.:.|     :|::.....:|:
Mouse   176 TTIEVFEHI---------------------NLMTLDIIMKCAFGQETNCQINGTYESYVKATFEL 219

  Fly   213 GQSLVFSRGLQFFKF--MLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPD-- 273
            |: ::.||...|:..  ::..|.||.....:|    ...:..:...:::..:...|:.:.:.|
Mouse   220 GE-IISSRLYNFWHHHDIIFKLSPKGHCFQEL----GKVIHQYTEKIIQDRKKILKNQVKQDDTQ 279

  Fly   274 ----MIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEI 334
                .:.:::.|:.|.|..::|.::.|:...|.:|..:.::..|....|.|..||:.|:|...||
Mouse   280 TSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEI 344

  Fly   335 VETKKAL-NGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVG 398
               :..| :|:.:|::.:.:|:|..|.|.|:||......:..|..||..||  .||..|   ..|
Mouse   345 ---RSILGDGSSITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTL--PDGHSL---PAG 401

  Fly   399 DRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGML 463
            ..:.:.|.|||.:...:.:|:.|||.||::|......|..:|||..|||||||.::|::::|..:
Mouse   402 MTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAI 466

  Fly   464 FNLLLHYKIEASPRTIKDLWGSASGFNFT---PRSGFWMHL 501
            ..:|||:::  :|    ||....:..:.|   |:.|.::||
Mouse   467 ALILLHFQV--AP----DLTRPPAFSSHTVLRPKHGIYLHL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	121/490 (25%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	117/476 (25%)