DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b2 and Cyp4f14

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_001191262.1	Gene:	Cyp4f14 / 64385	MGIID:	1927669	Length:	524	Species:	Mus musculus

Alignment Length:	493	Identity:	119/493 - (24%)
Similarity:	192/493 - (38%)	Gaps:	112/493 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KLVG--------FFNMRTPMITLNDPELIKK-------VCVKDFDHFPNHQPFITSNDRLFNDML 119
            :|||        :.....|:|||...::::.       |.:||...:...:|::       .|.|
Mouse    79 RLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYSILKPWL-------GDGL 136

  Fly   120 SVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESF-----------------AECLQH-----LD 162
            .|....:|...|..|||.|....::....:.|:|.                 .:..:|     ||
Mouse   137 LVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHVSLMTLD 201

  Fly   163 SSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKF 227
            |..|.:     |..|..  |.:.|::.||.                ..|: .:||..|..|...|
Mouse   202 SLQKCV-----FSFDSN--CQEKSSEYIAA----------------ILEL-SALVAKRHQQPLMF 242

  Fly   228 M--LSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRP-----------------D 273
            |  |..|.|......|.    ...|..|...|:     ||:|. |.|                 |
Mouse   243 MDLLYNLTPDGMRFRKA----CNVVHEFTDAVI-----RERHR-TLPDQGLDDFLKSKAKSKTLD 297

  Fly   274 MIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETK 338
            .|.:|:.:|:|...:.:|::|.|:...|.|...:..::.:....|.|..:|:.|||..:|:.|..
Mouse   298 FIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELL 362

  Fly   339 KALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINI 403
            :......:.:|.:.::.::.|.|.||||.........|.|::|..|  .||..:   ..|....|
Mouse   363 RGREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILL--PDGRTI---PKGIICLI 422

  Fly   404 PISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLL 468
            .|.|:|.:...:|:|..:||.||..|...|..|..::||..|||||||..:|:.::|..|...||
Mouse   423 SIFGIHHNPSVWPDPEVYDPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLL 487

  Fly   469 HYKI---EASPRTIKDLWGSASGFNFTPRSGFWMHLVP 503
            .:::   :..||...:|...|.|       |.|:.:.|
Mouse   488 RFRLLPDDKEPRRQPELILRAEG-------GLWLRVEP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	112/466 (24%)
Cyp4f14	NP_001191262.1	p450	52..511	CDD:365848	116/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900