Protein Alignment Cyp9b2 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 496
• Identity: 162/496 - (32%)
• Similarity: 265/496 - (53%)
• Gaps: 54/496 - (10%)

  Fly     4 IEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEF----YE 64
            |:..:.||......|.:.|.:...|::..:...||.|..||:.       ::...:.:|    |:
Mouse     9 IQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNII-------NYLDGMWKFDDDCYK 66

  Fly    65 RTRQHKLVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDMLSVMRDQRWK 128
              :..|:.||:....|::.:.|||:||.|.||: :..|.|.:||  .........:::..|:.||
Mouse    67 --KYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPF--GPVGFLKKSITISEDEEWK 127

  Fly   129 HMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATT 193
            .:|..|:|.||::|::.||.:|.:.....:::|....:     |...::||.:....|.|:|..|
Mouse   128 RLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEE-----KEEPINMKDIFGAYSMDVITGT 187

  Fly   194 AFGLKVNSYDNPKNEFYE-IGQSLVFSRGLQFF-KFMLST-----LVPKLFSLLKLTIFDSAKVD 251
            :.|:.::|.:||::.|.: |.:.|.|    :|| .|:||.     |.| ::.:|.|:||....::
Mouse   188 SCGVNIDSLNNPQDPFVQKIKKILKF----KFFDPFLLSVVLFPFLTP-IYEMLNLSIFPRQSMN 247

  Fly   252 YFARLV----VEAMQYREKHNITRPDMIQLLMEAKN----ESEDKWTDDEIVAQCFIFFFAAFEN 308
            :|.:.|    .:.:.|.:|:   |.|.:||:|..:|    ||....:|.|:.||..||.|..::.
Mouse   248 FFKKFVKKMKKDRLDYNQKN---RVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGGYDG 309

  Fly   309 NSNLICTTTYELLYNPDVQERLYEEIVETKKAL-NGAPLTYDAVQKMTYMDMVISESLRKWTLAA 372
            .|..|....|||..:||||::|.:||   .:|| |.||:||||:..|.|:|||::||||.:.:.:
Mouse   310 TSTSISFIMYELATHPDVQKKLQDEI---DRALPNKAPVTYDALMDMEYLDMVVNESLRLYPVVS 371

  Fly   373 ATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPY 437
            ..||...||..:..     :|..| |..:.|||..||.|..|:|||..|.|:|||:|.||::.||
Mouse   372 RIDRFSKKDVEIHG-----VFIPK-GTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPY 430

  Fly   438 TYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRT 478
            .|:|||.|||||||.|:||:.||..:..:|.::.::....|
Mouse   431 IYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEET 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	149/429 (35%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	149/429 (35%)