Protein Alignment Cyp9b2 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 493
• Identity: 156/493 - (31%)
• Similarity: 262/493 - (53%)
• Gaps: 48/493 - (9%)

  Fly     4 IEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYE--RT 66
            ||..:.||....|.|.:.|.:...|::..:...||.|.:|.:       .::...:.:|.|  ..
Mouse     9 IETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTI-------FNYYDGMWKFDEDCYK 66

  Fly    67 RQHKLVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDM------LSVMRD 124
            :..|:.||:....|::.:.|||:||.|.||: :..|        :|.|.|..:      :::..|
Mouse    67 KYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVF--------TNRRFFGPVGFMKKAITISED 123

  Fly   125 QRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDI 189
            :.||.:|..|:|.||:.|::.||.:|.:.....:::|....:     ||..:.||.:....|.|:
Mouse   124 EEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEE-----KGEPISMKDIFGAYSMDV 183

  Fly   190 IATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTL----VPKLFSLLKLTIFDSAKV 250
            |..|:||:.|:|.:||::.|.:..:.::  :...|..|:||.:    :..::.:|..:||....:
Mouse   184 ITGTSFGVNVDSLNNPQDPFVQKAKKIL--KFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSM 246

  Fly   251 DYFARLVVEAMQYREKHN-ITRPDMIQLLMEAKN----ESEDKWTDDEIVAQCFIFFFAAFENNS 310
            ::|.:.|....:.|...| ..|.|.:||:|..:|    ||:...:|.|:.||..||.|..::..|
Mouse   247 NFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGYDATS 311

  Fly   311 NLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATD 375
            ..|....|||..:||||::|.:||..|..  |.||:||||:..|.|:|||::||||.:.:|...:
Mouse   312 TSISLIMYELATHPDVQKKLQDEIDRTLP--NKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLE 374

  Fly   376 RLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYL 440
            |:..||..:..     :|..| |..:.|||..||.:..|:|||::|.|:|||:|.||::.||.|:
Mouse   375 RVSKKDVEING-----VFIPK-GTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYM 433

  Fly   441 PFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRT 478
            |||.|||||||.|:||:.:|..:..:|.::.::....|
Mouse   434 PFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEET 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	142/428 (33%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	142/428 (33%)