DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9b2 and Cyp4f1

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_062569.2	Gene:	Cyp4f1 / 56266	RGDID:	70926	Length:	524	Species:	Rattus norvegicus

Alignment Length:	508	Identity:	117/508 - (23%)
Similarity:	197/508 - (38%)	Gaps:	96/508 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RQLTEFYERTRQHKLVGFFNMRT----------------------------PMITLNDPELIKK- 92
            |:|..|.:..:::.|:|...|.|                            |:|||...::::.
  Rat    46 RRLRGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSI 110

  Fly    93 ------VCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMN 151
                  |.:||...:...:|::       .|.|.|....:|...|..|||.|....::....:.|
  Rat   111 LNASAAVALKDVIFYTILKPWL-------GDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFN 168

  Fly   152 ESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQ-- 214
            :|    ...:.:..|.|.......:||....:.::.|.:....|....|..:........|.:
  Rat   169 DS----TNIMHAKWKRLISEGSSRLDMFEHVSLMTLDSLQKCVFSFDSNCQEKSSEYIAAILELS 229

  Fly   215 SLVFSRGLQFFKFM--LSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQ--YREKHNITRP--- 272
            :||..|..|...||  |..|.|           |..:......||.|...  .||:.. |.|
  Rat   230 ALVAKRHQQPLLFMDLLYNLTP-----------DGMRFHKACNLVHEFTDAVIRERRR-TLPDQG 282

  Fly   273 --------------DMIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYN 323
                          |.|.:|:..|:|...:.:|::|.|:...|.|...:..::.:....|.|..:
  Rat   283 LDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKH 347

  Fly   324 PDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDD 388
            |:.|||..:|:.|..:..:...:.:|.:.::.::.|.|.||||.........|.|::|..|  .|
  Rat   348 PEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILL--PD 410

  Fly   389 GTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNR 453
            |..:   ..|....|.|.|:|.:...:|:|..::|.||..|...|..|..::||..|||||||..
  Rat   411 GRTI---PKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQT 472

  Fly   454 YALMQVKGMLFNLLLHYKI---EASPRTIKDLWGSASGFNFTPRSGFWMHLVP 503
            :|:.::|..|...||.:::   :..||...:|...|.|       |.|:.:.|
  Rat   473 FAMSEMKVALALTLLRFRLLPDDKEPRRQPELILRAEG-------GLWLRVEP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	110/481 (23%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	109/475 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900