Protein Alignment Cyp9b2 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 517
• Identity: 172/517 - (33%)
• Similarity: 281/517 - (54%)
• Gaps: 50/517 - (9%)

  Fly     6 ICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEF----YERT 66
            :.||::::  |:|::.|.|...|:::.:...||.||:|.:.       ::.:.|.:|    ||
Mouse    13 VLLAIILV--LLYRYGTRTHGLFKKQGIPGPKPLPFLGTVL-------NYYKGLWKFDMECYE-- 66

  Fly    67 RQHKLVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHM 130
            :..|..|.|:.:.|:..:.|||:||.|.||: |..|.|.:.|  ....:.:..:|:.:|:.||..
Mouse    67 KYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREF--GPVGIMSKAISISKDEEWKRY 129

  Fly   131 RNTLTPVFTAAKMRNMFTLMNESFAECL-QHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTA 194
            |..|:|.||:.|::.||.:: |.:.:.| ::|...::     ||..|.||.:....|.|:|.:|:
Mouse   130 RALLSPTFTSGKLKEMFPVI-EQYGDILVKYLMQEAE-----KGKPVTMKDVLGAYSIDVITSTS 188

  Fly   195 FGLKVNSYDNPKNEFYEIGQSLV---FSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARL 256
            ||:.|:|.:||::.|.|..:.::   |...|.|...:...|.| ::.:|.:.:|....:::|.:.
Mouse   189 FGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTP-VYEMLNICMFPKDSIEFFKKF 252

  Fly   257 VVEAMQYR----EKHNITRPDMIQLLMEAKNESEDK-----WTDDEIVAQCFIFFFAAFENNSNL 312
            |....:.|    :||   |.|.:||:|.|.|.|:||     .:|.||.||..:|.||.:|..|:.
Mouse   253 VNRMKESRLDSKQKH---RVDFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFAGYETTSST 314

  Fly   313 ICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRL 377
            :..|.|.|..:||:|::|.|||.||..  |.||.|||.|.:|.|:|||::|:||.:.:....:|.
Mouse   315 LSFTLYCLATHPDIQKKLQEEIDETLP--NKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERF 377

  Fly   378 CSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPF 442
            |.||..|   :|..:   ..|..:.||...||.|.:::|||.:|.|:|||:|.||.:.||.|:||
Mouse   378 CKKDVEL---NGVYI---PKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPF 436

  Fly   443 GVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPR 504
            |:|||||||.|:|.|.:|..|..::.::..:....|...|..|..|. ..|.....:.:|||
Mouse   437 GIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGL-LQPEKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	153/444 (34%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	153/446 (34%)