DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9b2 and Cyp6a14

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_001286199.1	Gene:	Cyp6a14 / 35835	FlyBaseID:	FBgn0033302	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	169/517 - (32%)
Similarity:	256/517 - (49%)	Gaps:	34/517 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTR 67
            |..|.|..||:| |.|......|..::.:.:..|.|.|.|||| ...::|..|:......|::.:
  Fly     2 LFTIALVGVVLG-LAYSLHIKIFSYWKRKGVPHETPLPIVGNM-RGIVKKYHFRDINQRIYKKFK 64

  Fly    68 -QHKLVG--FFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKH 129
             |..:.|  .|..||.:||  |.:.||:|.:|||.:|.:...|....|......|..:..:.|:.
  Fly    65 GQGPIAGMYMFFKRTALIT--DLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRA 127

  Fly   130 MRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTA 194
            ||:.||||||:.|::.|..::.:........:|.:.|.....:| .|::|.:|.:.:.|:|.:.|
  Fly   128 MRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEG-NVEIKDLCARFTTDVIGSCA 191

  Fly   195 FGLKVNSYDNPKNEFYEIGQSLVFSRG-----LQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFA 254
            |||:.||..:|..||.:.|:. :|:|.     :|.|.|..:.|..|    |::.:.......:|.
  Fly   192 FGLECNSLQDPSAEFRQKGRE-IFTRRRHSTLVQSFIFTNARLARK----LRIKVLPDDLTQFFM 251

  Fly   255 RLVVEAMQYREKHNITRPDMIQLLMEAKNESEDK------------WTDDEIVAQCFIFFFAAFE 307
            ..|...:.||.|:.|.|.|.|:.::|.:.|.::.            .|.:::.||.|:||.|.||
  Fly   252 STVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFE 316

  Fly   308 NNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAA 372
            .:|:.:....|||...||:|:||.|||......::|..|.||.:.:|||:|.|:||:|||..|..
  Fly   317 TSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLP 381

  Fly   373 ATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPY 437
            ...|..:|||.:.:.|    .....|....||:..:|.|...:|||.||||.||..|...:..|.
  Fly   382 HLIRETTKDYQIPNSD----IVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPM 442

  Fly   438 TYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWM 499
            .|||||.|||||||.|:..:|.|..|.:||..:|...|.||...|..|...|..|...|.::
  Fly   443 AYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	152/460 (33%)
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	160/486 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.970