Protein Alignment Cyp9b2 and Cyp3a44

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 516
• Identity: 168/516 - (32%)
• Similarity: 279/516 - (54%)
• Gaps: 48/516 - (9%)

  Fly     6 ICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTRQHK 70
            :.||::::  |:|::.|.|...|:::.:...||.||:|.:.........|..:..|.|.:|
Mouse    13 VLLAIILV--LLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYTGIWKFDMECYEKYGKT---- 71

  Fly    71 LVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRNTL 134
             .|.|:.:||::.:.|||.||.|.||| ...|.|.:.|  ....:.:..:|:.:|:.||..|..|
Mouse    72 -WGLFDGQTPLLVITDPETIKNVLVKDCLSVFTNRREF--GPVGIMSKAISISKDEEWKRYRALL 133

  Fly   135 TPVFTAAKMRNMFTLMNESFAECL-QHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLK 198
            :|.||:.:::.||.:: |.:.:.| ::|...::     ||..|.||.:....|.|:|.:|:||:.
Mouse   134 SPTFTSGRLKEMFPVI-EQYGDILVKYLRQEAE-----KGMPVAMKDVLGAYSMDVITSTSFGVN 192

  Fly   199 VNSYDNPKNEFYEIGQSLVFSRGLQF-----FKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVV 258
            |:|.:||::.|.|  ::..|.| :.|     |..:|..|:..::.:|.:.:|.:..:::|.:.|.
Mouse   193 VDSLNNPEDPFVE--EAKKFLR-VDFFDPLLFSVVLFPLLTPVYEMLNICMFPNDSIEFFKKFVD 254

  Fly   259 EAMQYR----EKHNITRPDMIQLLMEAKNESEDK-----WTDDEIVAQCFIFFFAAFENNSNLIC 314
            ...:.|    :||   |.|.:||:|.:.|.|:||     :::.||..|..||..|.:|..|:.:.
Mouse   255 RMQESRLDSNQKH---RVDFLQLMMNSHNNSKDKDSHKAFSNMEITVQSIIFISAGYETTSSTLS 316

  Fly   315 TTTYELLYNPDVQERLYEEIVETKKAL-NGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLC 378
            .|.|.|..:||:|::|..||   .||| |.|..|.|.|.:|.|:|||::|:||.:.:....:|:|
Mouse   317 FTLYCLATHPDIQKKLQAEI---DKALPNKATPTCDTVMEMEYLDMVLNETLRLYPIVTRLERVC 378

  Fly   379 SKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFG 443
            .||..|   :|..:   ..|..:.||...||.|.:::|:|.:|.|:|||:|.||.:.||.|||||
Mouse   379 KKDVEL---NGVYI---PKGSMVMIPSYALHHDPQHWPDPEEFQPERFSKENKGSIDPYVYLPFG 437

  Fly   444 VGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPR 504
            :|||||||.|:|||.:|..:..:|.::..:....|...|..|..|. ..|.....:.:|||
Mouse   438 IGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIPLKLSRQGI-LQPEKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	149/447 (33%)
Cyp3a44	NP_796354.1	CYP3A	67..493	CDD:410743	151/454 (33%)